HitPredict

Interactor 1: YAF2 (Q99LW6)
YY1-associated factor 2
Gene: YAF2

Interactor 2: RING2 (Q9CQJ4)
E3 ubiquitin-protein ligase RING2 (EC 2.3.2.27) (RING finger protein 1B) (RING1b) (RING finger protein 2) (RING-type E3 ubiquitin transferase RING2)
Gene: Rnf2

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.47	1.00	0.691

Property	Details
Experiments	17296600
Identification Methods	affinity chromatography technology, pull down
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	RAWUL~YAF2_RYBP
Common GO terms	GO:0005634 - nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 179 Mm			1 336
+	Hs
		1222214 YAF2_HUMAN (1-179): 4.9e-71: 214: 88.89		RING2_HUMAN (1-336): 2.74e-106: 315: 99.70
+	Mm
		1208123 RYBP_MOUSE (1-178): 1.04e-44: 149: 54.67		RING2_MOUSE (1-336): 2.13e-106: 316: 100.00
+	Hs
		987989 YAF2_HUMAN (1-179): 4.9e-71: 214: 88.89		RING1_HUMAN (10-336): 3.44e-66: 215: 51.75
+	Hs
		1222219 YAF2_HUMAN (1-179): 4.9e-71: 214: 88.89		PCGF6_HUMAN (30-293): 1.72e-44: 157: 15.36
+	Mm
		193411 RYBP_MOUSE (1-178): 1.04e-44: 149: 54.67		RING1_MOUSE (10-336): 8.61e-69: 222: 52.00
+	Hs
		1108516 YAF2_HUMAN (1-179): 4.9e-71: 214: 88.89		PCGF3_HUMAN (36-334): 2.56e-43: 151: 17.16
+	Hs
		718000 YAF2_HUMAN (1-179): 4.9e-71: 214: 88.89		BMI1_HUMAN (34-332): 2.52e-42: 151: 16.83
+	Hs
		718409 YAF2_HUMAN (1-179): 4.9e-71: 214: 88.89		PCGF2_HUMAN (34-332): 3.57e-40: 145: 15.51
+	Hs
		1197569 YAF2_HUMAN (1-179): 4.9e-71: 214: 88.89		PCGF5_HUMAN (34-334): 2.53e-39: 141: 18.24
+	Hs
		1019331 YAF2_HUMAN (1-179): 4.9e-71: 214: 88.89		TRI26_HUMAN (36-283): 2.67e-35: 136: 17.05
+	Hs
		1222217 YAF2_HUMAN (1-179): 4.9e-71: 214: 88.89		PCGF1_HUMAN (28-336): 1.37e-35: 131: 16.56
+	Dm
		1374687 Q9W215_DROME (1-133): 2.24e-53: 168: 49.62		Q9VV77_DROME (36-334): 4.84e-45: 155: 18.69
+	Dm
		728817 Q9W215_DROME (1-133): 2.24e-53: 168: 49.62		PSC_DROME (4-336): 6.6e-34: 134: 16.77
+	Mm
		1208122 RYBP_MOUSE (1-178): 1.04e-44: 149: 54.67		PCGF6_MOUSE (31-293): 9.54e-43: 152: 16.17
+	Hs
		718013 RYBP_HUMAN (1-178): 1.65e-44: 148: 54.67		BMI1_HUMAN (34-332): 2.52e-42: 151: 16.83
+	Mm
		620789 RYBP_MOUSE (1-178): 1.04e-44: 149: 54.67		PCGF2_MOUSE (34-332): 1.26e-37: 139: 16.17
+	Hs
		585013 RYBP_HUMAN (1-178): 1.65e-44: 148: 54.67		RO52_HUMAN (36-249): 1.63e-36: 139: 13.08
+	Mm
		1208119 RYBP_MOUSE (1-178): 1.04e-44: 149: 54.67		PCGF1_MOUSE (28-336): 1.86e-34: 128: 16.24
+	Hs
		536924 RYBP_HUMAN (1-178): 1.65e-44: 148: 54.67		TRI27_HUMAN (36-244): 3.8e-32: 127: 14.22
+	Dm
		1361718 Q9W215_DROME (1-133): 2.24e-53: 168: 49.62		RING1_DROME (204-333): 1.12e-19: 91.3: 40.15