HitPredict

Interactor 1: SYTL1 (Q99N80)
Synaptotagmin-like protein 1 (Exophilin-7)
Gene: SYTL1

Interactor 2: RB27A (Q9ERI2)
Ras-related protein Rab-27A (EC 3.6.5.2)
Gene: Rab27a

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	11773082
Identification Methods	coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0006887 - exocytosis GO:0016192 - vesicle-mediated transport GO:0042470 - melanosome GO:0070382 - exocytic vesicle
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 567 Mm			1 221
+	Hs
		845936 SYTL1_HUMAN (1-566): 9.1e-143: 425: 80.63		RB27A_HUMAN (1-221): 3.76e-82: 245: 95.93
+	Hs
		119861 SYTL1_HUMAN (1-566): 9.1e-143: 425: 80.63		RB27B_HUMAN (1-221): 6e-78: 234: 71.95
+	Hs
		894765 SYTL1_HUMAN (1-566): 9.1e-143: 425: 80.63		RAB8A_HUMAN (6-187): 9.19e-54: 172: 46.70
+	Mm
		1322328 SYTL4_MOUSE (71-566): 3.01e-99: 317: 29.03		RB27A_MOUSE (1-221): 3.76e-82: 245: 100.00
+	Hs
		129082 SYT5_HUMAN (260-546): 7.1e-104: 319: 27.30		RAB1A_HUMAN (1-219): 3.6e-80: 240: 34.84
+	Hs
		845942 SYTL4_HUMAN (71-563): 7.34e-98: 313: 30.00		RB27A_HUMAN (1-221): 3.76e-82: 245: 95.93
+	Mm
		1307925 SYTL4_MOUSE (71-566): 3.01e-99: 317: 29.03		RB27B_MOUSE (1-221): 4.19e-77: 232: 71.49
+	Hs
		119867 SYTL4_HUMAN (71-563): 7.34e-98: 313: 30.00		RB27B_HUMAN (1-221): 6e-78: 234: 71.95
+	Hs
		914274 SYTL4_HUMAN (71-563): 7.34e-98: 313: 30.00		RB11A_HUMAN (3-220): 2.86e-77: 233: 34.84
+	Mm
		722679 RP3A_MOUSE (97-548): 7.01e-88: 287: 19.75		RAB3D_MOUSE (2-221): 1.04e-85: 254: 40.46
+	Hs
		1134943 SYT6_HUMAN (127-559): 3.07e-94: 299: 19.41		RAB1B_HUMAN (3-219): 2.96e-79: 237: 34.56
+	Hs
		896633 SYT6_HUMAN (127-559): 3.07e-94: 299: 19.41		RAB14_HUMAN (2-221): 5.51e-77: 232: 31.39
+	Mm
		926098 SYTL4_MOUSE (71-566): 3.01e-99: 317: 29.03		RAB3A_MOUSE (2-192): 9.5e-57: 181: 43.98
+	Hs
		591484 SYTL4_HUMAN (71-563): 7.34e-98: 313: 30.00		RAB3A_HUMAN (2-192): 8.9e-57: 181: 43.98
+	Hs
		320135 SYTL4_HUMAN (71-563): 7.34e-98: 313: 30.00		RAB3D_HUMAN (2-190): 1.75e-56: 180: 43.92
+	Mm
		877205 SYTL4_MOUSE (71-566): 3.01e-99: 317: 29.03		RAB8A_MOUSE (6-187): 1.15e-53: 172: 46.70
+	Hs
		591654 SYTL4_HUMAN (71-563): 7.34e-98: 313: 30.00		RAB3B_HUMAN (2-190): 1.87e-54: 175: 43.92
+	Hs
		894790 SYTL4_HUMAN (71-563): 7.34e-98: 313: 30.00		RAB8A_HUMAN (6-187): 9.19e-54: 172: 46.70
+	Hs
		1273004 SYTL4_HUMAN (71-563): 7.34e-98: 313: 30.00		RAB8B_HUMAN (6-192): 3.9e-53: 171: 44.39
+	Mm
		812770 RP3A_MOUSE (97-548): 7.01e-88: 287: 19.75		RAB8A_MOUSE (6-187): 1.15e-53: 172: 46.70