HitPredict

Interactor 1: CAD23 (Q99PF4)
Cadherin-23 (Otocadherin)
Gene: Cdh23

Interactor 2: PCD15 (Q99PJ1)
Protocadherin-15
Gene: Pcdh15

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.82 1.00 0.908

The method score is based on:

Property Details
Experiments 17805295, 19270079, 23135401, 20498078
Identification Methods pull down, isothermal titration calorimetry, molecular sieving, transmission electron microscopy, x-ray crystallography
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Cadherin~Cadherin, Cadherin~ECD
Common GO terms GO:0005509 - calcium ion binding
GO:0005886 - plasma membrane
GO:0007155 - cell adhesion
GO:0007156 - homophilic cell adhesion via plasma membrane adhesion molecules
GO:0007605 - sensory perception of sound
and 6 others

more...
Homologous interactions 19

Homologous interactions

Color coding for hit scores

1 3354
Mm

1 1943
+ Mm
+ Mm
+ Hs
+ Dm
+ Hs
+ Dm
+ Dm
+ Hs
+ Hs
+ Hs
+ Hs
+ Dm
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024