HitPredict

Interactor 1: RGS18 (Q99PG4)
Regulator of G-protein signaling 18 (RGS18)
Gene: RGS18

Interactor 2: GNAI3 (Q9DC51)
Guanine nucleotide-binding protein G(i) subunit alpha-3 (G(i) alpha-3)
Gene: GNAI3

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	11342430
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	G-alpha~RGS
Common GO terms	GO:0005737 - cytoplasm GO:0007186 - G protein-coupled receptor signaling pathway
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 235 Mm			1 354
+	Hs
		926720 RGS18_HUMAN (1-235): 7.67e-91: 268: 83.83		GNAI1_HUMAN (1-354): 2.68e-178: 500: 93.79
+	Hs
		444800 RGS18_HUMAN (1-235): 7.67e-91: 268: 83.83		GNAI3_HUMAN (1-354): 6.59e-176: 494: 98.31
+	Hs
		391473 RGS18_HUMAN (1-235): 7.67e-91: 268: 83.83		GNAI2_HUMAN (1-354): 4.82e-174: 489: 85.35
+	Hs
		444693 RGS7_HUMAN (23-234): 3.05e-75: 237: 24.77		GNAI3_HUMAN (1-354): 6.59e-176: 494: 98.31
+	Hs
		444692 RGS3_HUMAN (30-211): 8.39e-70: 233: 41.76		GNAI3_HUMAN (1-354): 6.59e-176: 494: 98.31
+	Mm
		597637 RGS18_MOUSE (1-235): 2.21e-90: 267: 100.00		GNAQ_MOUSE (1-353): 5.81e-161: 456: 50.85
+	Hs
		837653 RGS18_HUMAN (1-235): 7.67e-91: 268: 83.83		GNAQ_HUMAN (1-353): 1.06e-160: 455: 50.85
+	Hs
		391357 RGS3_HUMAN (30-211): 8.39e-70: 233: 41.76		GNAI2_HUMAN (1-354): 4.82e-174: 489: 85.35
+	Hs
		444680 RGS2_HUMAN (4-206): 6.01e-71: 217: 43.35		GNAI3_HUMAN (1-354): 6.59e-176: 494: 98.31
+	Hs
		277782 RGS9_HUMAN (17-235): 1.51e-70: 229: 25.78		GNAO_HUMAN (1-354): 3.97e-170: 479: 71.27
+	Hs
		391358 RGS4_HUMAN (38-224): 8.82e-66: 204: 40.96		GNAI2_HUMAN (1-354): 4.82e-174: 489: 85.35
+	Hs
		834946 RGS7_HUMAN (23-234): 3.05e-75: 237: 24.77		GNAQ_HUMAN (1-353): 1.06e-160: 455: 50.85
+	Bt
		221230 RGS9_BOVIN (17-235): 8.34e-71: 225: 26.22		GNAT1_BOVIN (1-354): 2.34e-163: 462: 64.69
+	Hs
		450989 RGS4_HUMAN (38-224): 8.82e-66: 204: 40.96		GNAO_HUMAN (1-354): 3.97e-170: 479: 71.27
+	Hs
		580410 RGS7_HUMAN (23-234): 3.05e-75: 237: 24.77		GNAZ_HUMAN (1-353): 5.54e-155: 440: 66.95
+	Hs
		670435 RGS3_HUMAN (30-211): 8.39e-70: 233: 41.76		GNA11_HUMAN (1-353): 3.67e-156: 443: 50.00
+	Hs
		782018 RGS2_HUMAN (4-206): 6.01e-71: 217: 43.35		GNAQ_HUMAN (1-353): 1.06e-160: 455: 50.85
+	Hs
		834936 RGS4_HUMAN (38-224): 8.82e-66: 204: 40.96		GNAQ_HUMAN (1-353): 1.06e-160: 455: 50.85
+	Hs
		675585 RGS2_HUMAN (4-206): 6.01e-71: 217: 43.35		GNA15_HUMAN (4-353): 9.74e-143: 410: 42.54
+	Hs
		782024 RGS2_HUMAN (4-206): 6.01e-71: 217: 43.35		GNAS2_HUMAN (1-353): 2.86e-138: 400: 38.17