HitPredict

Interactor 1: PSDE (O00487)
26S proteasome non-ATPase regulatory subunit 14 (EC 3.4.19.-) (26S proteasome regulatory subunit RPN11) (26S proteasome-associated PAD1 homolog 1)
Gene: PSMD14

Interactor 2: RD23B (P54727)
UV excision repair protein RAD23 homolog B (HR23B) (hHR23B) (XP-C repair-complementing complex 58 kDa protein) (p58)
Gene: RAD23B

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.68	1.00	0.827

Property	Details
Experiments	27114451, 35530310, 17323924
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	JAB~ubiquitin
Common GO terms	GO:0000502 - proteasome complex GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol GO:0043161 - proteasome-mediated ubiquitin-dependent protein catabolic process and 1 others more... GO:0070628 - proteasome binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 310 Hs			1 409
+	Rn
		1117318 Q4V8E2_RAT (1-310): 1.28e-110: 324: 100.00		RD23B_RAT (1-409): 1.14e-120: 358: 87.23
+	Hs
		130813 PSDE_HUMAN (1-310): 1.28e-110: 324: 100.00		RD23A_HUMAN (1-409): 9.12e-94: 287: 56.72
+	Hs
		131106 PSDE_HUMAN (1-310): 1.28e-110: 324: 100.00		UBQL1_HUMAN (1-404): 1.25e-57: 200: 13.72
+	Sc
		697094 RPN11_YEAST (1-310): 1.59e-93: 281: 64.84		RAD23_YEAST (1-407): 2.12e-72: 233: 28.41
+	Zm
		27878 B4FLQ8_MAIZE (1-309): 4.83e-111: 326: 79.29		A0A1D6JMS0_MAIZE (2-407): 1.23e-51: 183: 15.43
+	Hs
		131100 PSDE_HUMAN (1-310): 1.28e-110: 324: 100.00		UBQL2_HUMAN (1-364): 5.93e-51: 182: 13.68
+	Dm
		1358677 PSDE_DROME (1-310): 7.15e-114: 333: 88.39		Q9VWD9_DROME (1-353): 1.07e-44: 164: 11.08
+	Hs
		131091 PSDE_HUMAN (1-310): 1.28e-110: 324: 100.00		UBQL4_HUMAN (1-364): 2.75e-45: 166: 12.71
+	Mm
		192886 PSDE_MOUSE (1-310): 1.28e-110: 324: 100.00		UBC_MOUSE (1-118): 1.78e-32: 131: 21.67
+	Hs
		130704 PSDE_HUMAN (1-310): 1.28e-110: 324: 100.00		UBB_HUMAN (1-79): 1.99e-32: 123: 30.38
+	Hs
		130838 PSDE_HUMAN (1-310): 1.28e-110: 324: 100.00		RL40_HUMAN (1-91): 3.57e-33: 122: 28.57
+	At
		1092172 PSDE_ARATH (1-309): 1.07e-109: 322: 79.61		UBQ3_ARATH (1-80): 7.66e-29: 116: 28.75
+	Hs
		130837 PSDE_HUMAN (1-310): 1.28e-110: 324: 100.00		RS27A_HUMAN (1-90): 2.4e-15: 75: 26.67
+	Mm
		193512 CSN5_MOUSE (1-305): 4.65e-83: 255: 28.35		UBC_MOUSE (1-118): 1.78e-32: 131: 21.67
+	Zm
		46881 A0A3L6GBJ0_MAIZE (8-304): 3.94e-71: 226: 18.33		C0PFA7_MAIZE (2-407): 1.73e-38: 147: 13.85
+	At
		1091793 CSN5A_ARATH (2-303): 1.72e-80: 249: 29.78		UBQ3_ARATH (1-80): 7.66e-29: 116: 28.75
+	At
		1091965 EIF3H_ARATH (7-304): 4.37e-72: 227: 18.61		UBQ3_ARATH (1-80): 7.66e-29: 116: 28.75
+	At
		1091969 PSD7B_ARATH (15-256): 1.76e-49: 168: 18.43		UBQ3_ARATH (1-80): 7.66e-29: 116: 28.75
+	At
		188941 PSD7A_ARATH (15-256): 5.45e-49: 167: 18.04		UBQ3_ARATH (1-80): 7.66e-29: 116: 28.75
+	At
		1091838 AMSH1_ARATH (30-213): 1.94e-45: 162: 17.39		UBQ3_ARATH (1-80): 7.66e-29: 116: 28.75