HitPredict

Interactor 1: Q9BI72 (Q9BI72)
ENTH domain-containing protein
Gene: epn-1

Interactor 2: Q9U2T9 (Q9U2T9)
Intersectin-1
Gene: itsn-1

Species: Caenorhabditis elegans

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.68	0.60	0.639

Property	Details
Experiments	23424658, 18298590, 23549480
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0007015 - actin filament organization
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 467 Ce			1 1085
+	Ce
		1308343 Q9BI71_CAEEL (1-467): 1.4e-134: 398: 99.36		Q9U2T9_CAEEL (1-1085): 6.1e-161: 506: 100.00
+	Hs
		787913 EPN4_HUMAN (3-464): 3.38e-94: 299: 21.97		EPS15_HUMAN (4-576): 1.54e-61: 229: 18.12
+	Hs
		1353935 EPN1_HUMAN (1-455): 1.86e-83: 269: 32.91		EP15R_HUMAN (5-473): 6.97e-71: 256: 22.69
+	Hs
		787997 EPN1_HUMAN (1-455): 1.86e-83: 269: 32.91		EPS15_HUMAN (4-576): 1.54e-61: 229: 18.12
+	Dm
		91160 Q7KU90_DROME (1-438): 1.37e-83: 275: 37.39		E3CTP7_DROME (5-492): 4.03e-56: 211: 19.41
+	Hs
		787969 EPN3_HUMAN (1-467): 1.37e-75: 250: 32.59		EPS15_HUMAN (4-576): 1.54e-61: 229: 18.12
+	Hs
		557693 EPN4_HUMAN (3-464): 3.38e-94: 299: 21.97		NCK1_HUMAN (887-1082): 7.16e-35: 139: 22.27
+	Hs
		161630 GAK_HUMAN (151-463): 6.8e-32: 131: 12.54		EPS15_HUMAN (4-576): 1.54e-61: 229: 18.12
+	Hs
		787875 AGFG1_HUMAN (144-467): 6.96e-32: 129: 14.45		EPS15_HUMAN (4-576): 1.54e-61: 229: 18.12
+	Mm
		1194353 EPN1_MOUSE (1-455): 5.13e-83: 268: 33.33		ITSN1_MOUSE (780-940): 1.48e-14: 81: 26.95
+	Mm
		788005 AGFG1_MOUSE (144-467): 4.36e-32: 130: 13.47		EPS15_MOUSE (4-464): 1.55e-54: 208: 20.78
+	Sc
		710409 ENT1_YEAST (4-209): 7.78e-75: 243: 40.10		EDE1_YEAST (171-297): 9.84e-10: 65: 22.05
+	Hs
		203230 SYNJ1_HUMAN (169-467): 1.15e-11: 69.5: 9.75		SH319_HUMAN (722-1084): 1.39e-34: 144: 18.88
+	Hs
		854959 AGFG1_HUMAN (144-467): 6.96e-32: 129: 14.45		ITSN1_HUMAN (780-940): 3.98e-15: 82.9: 26.35
+	Hs
		203208 SYNJ1_HUMAN (169-467): 1.15e-11: 69.5: 9.75		NCK1_HUMAN (887-1082): 7.16e-35: 139: 22.27
+	Hs
		307533 EPN2_HUMAN (171-465): 4.82e-17: 85.7: 24.02		ITSN1_HUMAN (780-940): 3.98e-15: 82.9: 26.35
+	Hs
		203228 SYNJ1_HUMAN (169-467): 1.15e-11: 69.5: 9.75		ITSN1_HUMAN (780-940): 3.98e-15: 82.9: 26.35
+	Hs
		203218 SYNJ1_HUMAN (169-467): 1.15e-11: 69.5: 9.75		GRB2_HUMAN (1030-1085): 4.24e-13: 71.7: 33.33
+	Hs
		203192 SYNJ1_HUMAN (169-467): 1.15e-11: 69.5: 9.75		SRBS2_HUMAN (890-1084): 1.68e-09: 64.3: 27.20