Interactor 1: GRP3 (Q8IV61)
Ras guanyl-releasing protein 3 (Calcium and DAG-regulated guanine nucleotide exchange factor III) (Guanine nucleotide exchange factor for Rap1)
Gene: RASGRP3

Interactor 2: DYL2 (Q96FJ2)
Dynein light chain 2, cytoplasmic (8 kDa dynein light chain b) (DLC8b) (Dynein light chain LC8-type 2)
Gene: DYNLL2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.54 1.00 0.740

The method score is based on:

Property Details
Experiments 25416956
Identification Methods two hybrid, two hybrid prey pooling approach, two hybrid array, validated two hybrid
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Dynein_light~EF-hand_7
Common GO terms GO:0005886 - plasma membrane
Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 690
Hs

1 89
+ Hs

Service provided by Combinatics, Japan

Last updated: 11Aug2025