HitPredict

Interactor 1: B9D2 (Q9BPU9)
B9 domain-containing protein 2 (MKS1-related protein 2)
Gene: B9D2

Interactor 2: MKS1 (Q9NXB0)
Tectonic-like complex member MKS1 (Meckel syndrome type 1 protein)
Gene: MKS1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.71	0.60	0.656

Property	Details
Experiments	26638075, 33961781, 32726168
Identification Methods	proximity labelling technology, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005813 - centrosome GO:0005829 - cytosol GO:0016020 - membrane GO:0036038 - MKS complex GO:0036064 - ciliary basal body and 1 others more... GO:0060271 - cilium assembly
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 175 Hs			1 559
+	Mm
		1112799 B9D2_MOUSE (1-175): 1.36e-83: 245: 96.57		MKS1_MOUSE (1-557): 0: 954: 89.11
+	Mm
		1131721 B9D1_MOUSE (4-174): 1.09e-72: 219: 26.44		MKS1_MOUSE (1-557): 0: 954: 89.11
+	Hs
		1347888 B9D1_HUMAN (4-174): 3.2e-71: 215: 27.01		MKS1_HUMAN (1-559): 0: 958: 100.00
+	Hs
		1308512 B9D2_HUMAN (1-175): 5.49e-84: 246: 100.00		B9D1_HUMAN (307-496): 8.66e-66: 214: 25.79
+	Mm
		1112804 B9D2_MOUSE (1-175): 1.36e-83: 245: 96.57		B9D1_MOUSE (307-496): 9.03e-66: 214: 24.74
+	Ce
		1094113 Q9N423_CAEEL (1-175): 2.89e-77: 229: 43.43		Q21191_CAEEL (305-495): 1.61e-57: 193: 20.42
+	Mm
		1129452 MKS1_MOUSE (4-164): 2.68e-53: 179: 25.82		Q5NCM9_MOUSE (409-496): 4.89e-24: 99: 23.47