HitPredict

Interactor 1: DDX50 (Q9BQ39)
ATP-dependent RNA helicase DDX50 (EC 3.6.4.13) (DEAD box protein 50) (Gu-beta) (Nucleolar protein Gu2)
Gene: DDX50

Interactor 2: DDX21 (Q9NR30)
Nucleolar RNA helicase 2 (EC 3.6.4.13) (DEAD box protein 21) (Gu-alpha) (Nucleolar RNA helicase Gu) (Nucleolar RNA helicase II) (RH II/Gu)
Gene: DDX21

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.80 1.00 0.895

The method score is based on:

Property Details
Experiments 35271311, 34349018, 33961781, 37071682
Identification Methods affinity chromatography technology, cross-linking study, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains DEAD~DEAD, DEAD~Helicase_C, Helicase_C~Helicase_C
Common GO terms GO:0003723 - RNA binding
GO:0003724 - RNA helicase activity
GO:0003729 - mRNA binding
GO:0005524 - ATP binding
GO:0005730 - nucleolus
and 3 others

more...
Homologous interactions 15

Homologous interactions

Color coding for hit scores

1 737
Hs

1 783
+ Zm
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Sc
+ Sc
+ Hs
+ Hs
+ Sc
+ Hs
+ Ec

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Last updated: 15 Jul 2024