HitPredict

Interactor 1: MEP50 (Q9BQA1)
Methylosome protein WDR77 (Androgen receptor cofactor p44) (Methylosome protein 50) (MEP-50) (WD repeat-containing protein 77) (p44/Mep50)
Gene: WDR77

Interactor 2: PKHA4 (Q9H4M7)
Pleckstrin homology domain-containing family A member 4 (PH domain-containing family A member 4) (Phosphoinositol 3-phosphate-binding protein 1) (PEPP-1)
Gene: PLEKHA4

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	31091453
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PH~WD40
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 342 Hs			1 779
+	Hs
		793030 LIS1_HUMAN (62-339): 9.49e-75: 238: 16.72		PKHA4_HUMAN (1-779): 4.1e-157: 477: 100.00
+	Hs
		1319411 WDR33_HUMAN (58-331): 3.52e-67: 230: 17.86		PKHA4_HUMAN (1-779): 4.1e-157: 477: 100.00
+	Hs
		1331436 NLE1_HUMAN (114-333): 2.06e-53: 184: 18.05		PKHA4_HUMAN (1-779): 4.1e-157: 477: 100.00
+	Hs
		725559 COPB2_HUMAN (54-331): 3.17e-47: 172: 18.38		PKHA4_HUMAN (1-779): 4.1e-157: 477: 100.00
+	Hs
		1318178 TBL1R_HUMAN (206-337): 3.38e-19: 90.1: 13.01		PKHA4_HUMAN (1-779): 4.1e-157: 477: 100.00
+	Hs
		1309164 TBL1Y_HUMAN (207-337): 6.68e-19: 89.3: 14.38		PKHA4_HUMAN (1-779): 4.1e-157: 477: 100.00
+	Hs
		1153353 MEP50_HUMAN (1-342): 6.74e-81: 251: 100.00		PKHA7_HUMAN (2-440): 4.98e-50: 192: 28.02
+	Hs
		1167411 MEP50_HUMAN (1-342): 6.74e-81: 251: 100.00		MPRIP_HUMAN (2-499): 4.76e-44: 173: 16.57
+	Hs
		1022446 WDR33_HUMAN (58-331): 3.52e-67: 230: 17.86		TIAM1_HUMAN (2-634): 3.43e-44: 174: 12.28
+	Hs
		1153322 FBXW7_HUMAN (3-236): 5.23e-43: 159: 14.29		PKHA7_HUMAN (2-440): 4.98e-50: 192: 28.02
+	Hs
		1309278 MEP50_HUMAN (1-342): 6.74e-81: 251: 100.00		TARA_HUMAN (49-471): 7.83e-20: 97.3: 15.21
+	Hs
		1167395 FBXW7_HUMAN (3-236): 5.23e-43: 159: 14.29		MPRIP_HUMAN (2-499): 4.76e-44: 173: 16.57
+	Hs
		1148943 FBXW7_HUMAN (3-236): 5.23e-43: 159: 14.29		CYTSA_HUMAN (320-643): 3.92e-43: 171: 12.81
+	Hs
		725564 COPB2_HUMAN (54-331): 3.17e-47: 172: 18.38		PKHA5_HUMAN (2-653): 1.62e-36: 150: 17.61
+	Hs
		725566 COPB2_HUMAN (54-331): 3.17e-47: 172: 18.38		PKHA2_HUMAN (1-258): 2.68e-38: 149: 15.90
+	Sc
		784452 COPB2_YEAST (15-314): 1.99e-22: 100: 14.47		OSH2_YEAST (2-703): 2.25e-55: 208: 10.89
+	Hs
		725490 COPB2_HUMAN (54-331): 3.17e-47: 172: 18.38		RHG24_HUMAN (55-181): 6.43e-27: 119: 25.93
+	Hs
		1153371 TBL1R_HUMAN (206-337): 3.38e-19: 90.1: 13.01		PKHA7_HUMAN (2-440): 4.98e-50: 192: 28.02
+	Hs
		903302 WDR5_HUMAN (247-341): 5.14e-19: 88.2: 19.79		PKHA7_HUMAN (2-440): 4.98e-50: 192: 28.02
+	Hs
		1240465 POC1A_HUMAN (201-341): 1.98e-27: 112: 18.31		PKHA5_HUMAN (2-653): 1.62e-36: 150: 17.61