HitPredict

Interactor 1: MEP50 (Q9BQA1)
Methylosome protein WDR77 (Androgen receptor cofactor p44) (Methylosome protein 50) (MEP-50) (WD repeat-containing protein 77) (p44/Mep50)
Gene: WDR77

Interactor 2: PRC2C (Q9Y520)
Protein PRRC2C (BAT2 domain-containing protein 1) (HBV X-transactivated gene 2 protein) (HBV XAg-transactivated protein 2) (HLA-B-associated transcript 2-like 2) (Proline-rich and coiled-coil-containing protein 2C)
Gene: PRRC2C

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	28977470
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 342 Hs			1 2896
+	Hs
		1302927 NLE1_HUMAN (114-333): 2.06e-53: 184: 18.05		MINT_HUMAN (22-1891): 2.31e-43: 178: 9.12
+	Hs
		821018 MEP50_HUMAN (1-342): 6.74e-81: 251: 100.00		PRC2A_HUMAN (1183-2870): 8.38e-21: 103: 8.16
+	Hs
		793042 LIS1_HUMAN (62-339): 9.49e-75: 238: 16.72		SRRM2_HUMAN (10-1337): 2.52e-18: 95.2: 8.28
+	Hs
		1300916 MEP50_HUMAN (1-342): 6.74e-81: 251: 100.00		CIC_HUMAN (57-1435): 3.5e-10: 68.5: 9.73
+	Hs
		1281353 FBXW7_HUMAN (3-236): 5.23e-43: 159: 14.29		DIDO1_HUMAN (88-631): 5.4e-37: 156: 16.09
+	Hs
		1346974 NLE1_HUMAN (114-333): 2.06e-53: 184: 18.05		NCOR2_HUMAN (685-2896): 1.59e-24: 115: 7.48
+	Hs
		1346970 NLE1_HUMAN (114-333): 2.06e-53: 184: 18.05		SRRM2_HUMAN (10-1337): 2.52e-18: 95.2: 8.28
+	Dm
		248488 COPB2_DROME (22-239): 4.04e-34: 134: 15.70		Q9VLS7_DROME (1208-2548): 1.93e-23: 111: 9.16
+	Hs
		1057782 FBXW7_HUMAN (3-236): 5.23e-43: 159: 14.29		NCOA6_HUMAN (37-1027): 9.61e-13: 76.7: 7.69
+	Hs
		1281391 FBXW7_HUMAN (3-236): 5.23e-43: 159: 14.29		PRR36_HUMAN (57-1199): 1.33e-12: 76.2: 10.89
+	Hs
		245652 TBL1X_HUMAN (162-342): 3.97e-28: 116: 15.46		NCOR2_HUMAN (685-2896): 1.59e-24: 115: 7.48
+	Pf
		1211425 Q8I390_PLAF7 (128-323): 1.95e-15: 79.5: 14.29		Q8IBL1_PLAF7 (286-699): 2.58e-33: 143: 14.58
+	Dm
		1370295 POC1_DROME (201-335): 1.71e-23: 101: 19.12		Q9VLS7_DROME (1208-2548): 1.93e-23: 111: 9.16
+	Hs
		1309170 TBL1Y_HUMAN (207-337): 6.68e-19: 89.3: 14.38		NCOR2_HUMAN (685-2896): 1.59e-24: 115: 7.48
+	Hs
		820867 WDR5_HUMAN (247-341): 5.14e-19: 88.2: 19.79		PRC2A_HUMAN (1183-2870): 8.38e-21: 103: 8.16
+	Hs
		903374 WDR5_HUMAN (247-341): 5.14e-19: 88.2: 19.79		KMT2C_HUMAN (1901-2885): 8.54e-14: 80.6: 9.27
+	Hs
		1074805 TAF5_HUMAN (178-328): 1.2e-21: 98: 18.42		CIC_HUMAN (57-1435): 3.5e-10: 68.5: 9.73
+	Hs
		903229 WDR5_HUMAN (247-341): 5.14e-19: 88.2: 19.79		NCOA6_HUMAN (37-1027): 9.61e-13: 76.7: 7.69
+	Hs
		903450 WDR5_HUMAN (247-341): 5.14e-19: 88.2: 19.79		CIC_HUMAN (57-1435): 3.5e-10: 68.5: 9.73