Interactor 1: DPH2 (Q9BQC3)
2-(3-amino-3-carboxypropyl)histidine synthase subunit 2 (Diphthamide biosynthesis protein 2) (Diphtheria toxin resistance protein 2) (S-adenosyl-L-methionine:L-histidine 3-amino-3-carboxypropyltransferase 2)
Gene: DPH2

Interactor 2: DPH1 (Q9BZG8)
2-(3-amino-3-carboxypropyl)histidine synthase subunit 1 (EC 2.5.1.108) (Diphthamide biosynthesis protein 1) (Diphtheria toxin resistance protein 1) (Ovarian cancer-associated gene 1 protein) (S-adenosyl-L-methionine:L-histidine 3-amino-3-carboxypropyltransferase 1)
Gene: DPH1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.44 1.00 0.665

The method score is based on:

Property Details
Experiments 35271311
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Diphthamide_syn~Diphthamide_syn
Common GO terms GO:0005829 - cytosol
GO:0017183 - protein histidyl modification to diphthamide
GO:0032991 - protein-containing complex
GO:0046872 - metal ion binding
GO:0051539 - 4 iron, 4 sulfur cluster binding
and 1 others

more...

Homologous interactions 6

Homologous interactions

Color coding for hit scores

1 489
Hs

1 438
+ Mm
+ Dm
+ Ce
+ Sp
+ Sc
+ Ph

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024