HitPredict

Interactor 1: FYCO1 (Q9BQS8)
FYVE and coiled-coil domain-containing protein 1 (Zinc finger FYVE domain-containing protein 7)
Gene: FYCO1

Interactor 2: KLDC2 (Q9Y2U9)
Kelch domain-containing protein 2 (Hepatocellular carcinoma-associated antigen 33) (Host cell factor homolog LCP) (Host cell factor-like protein 1) (HCLP-1)
Gene: KLHDC2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.50	0.489

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 1478 Hs			1 406
+	Hs
		148556 CTRO_HUMAN (195-970): 2.82e-38: 159: 15.44		HCFC1_HUMAN (1-302): 6.46e-41: 157: 17.43
+	Hs
		725094 MYH9_HUMAN (1-843): 7.74e-35: 148: 11.32		NS1BP_HUMAN (122-404): 4.29e-37: 144: 11.01
+	Hs
		528383 MYH6_HUMAN (435-1366): 9.43e-35: 148: 12.14		LZTR1_HUMAN (162-401): 1.73e-32: 131: 13.83
+	Hs
		1049212 EEA1_HUMAN (1-910): 5.8e-37: 155: 10.89		KEAP1_HUMAN (226-406): 5.71e-30: 123: 15.76
+	Hs
		528416 MYH8_HUMAN (574-1306): 8.02e-28: 125: 13.48		LZTR1_HUMAN (162-401): 1.73e-32: 131: 13.83
+	Hs
		1235475 MYH4_HUMAN (574-1306): 1.38e-26: 121: 11.92		LZTR1_HUMAN (162-401): 1.73e-32: 131: 13.83
+	Hs
		522627 MYH7_HUMAN (1-631): 4.24e-24: 113: 8.32		LZTR1_HUMAN (162-401): 1.73e-32: 131: 13.83
+	Hs
		522613 MYH7_HUMAN (1-631): 4.24e-24: 113: 8.32		KEAP1_HUMAN (226-406): 5.71e-30: 123: 15.76
+	Hs
		1235465 MYH13_HUMAN (718-1330): 1.28e-21: 104: 11.35		LZTR1_HUMAN (162-401): 1.73e-32: 131: 13.83
+	Hs
		522559 MYH1_HUMAN (784-1367): 3.19e-17: 90.3: 9.42		LZTR1_HUMAN (162-401): 1.73e-32: 131: 13.83
+	Hs
		528428 MYH8_HUMAN (574-1306): 8.02e-28: 125: 13.48		KLHL9_HUMAN (265-402): 2.48e-13: 73.6: 15.07
+	Hs
		1049213 PLEC_HUMAN (385-1169): 2.58e-09: 64.7: 22.38		KEAP1_HUMAN (226-406): 5.71e-30: 123: 15.76
+	Hs
		522651 MYH7_HUMAN (1-631): 4.24e-24: 113: 8.32		KLHL9_HUMAN (265-402): 2.48e-13: 73.6: 15.07
+	Hs
		551745 DESP_HUMAN (232-1121): 6.82e-14: 79.7: 22.05		FBX42_HUMAN (212-366): 7.52e-22: 99.9: 25.00