HitPredict

Interactor 1: LZTS2 (Q9BRK4)
Leucine zipper putative tumor suppressor 2 (hLZTS2) (Protein LAPSER1)
Gene: LZTS2

Interactor 2: WDR33 (Q9C0J8)
pre-mRNA 3' end processing protein WDR33 (WD repeat-containing protein 33) (WD repeat-containing protein of 146 kDa)
Gene: WDR33

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.50	0.574

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 669 Hs			1 1336
+	Hs
		1145923 CP135_HUMAN (300-610): 1.6e-09: 63.5: 21.52		WDR33_HUMAN (1-1324): 2.65e-176: 561: 96.13
+	Dm
		1181503 Q9W3A1_DROME (293-475): 7.07e-42: 164: 28.80		LIS1_DROME (229-524): 2.27e-51: 189: 19.48
+	Hs
		1281510 MTCL1_HUMAN (56-644): 5.72e-34: 141: 14.24		FBXW7_HUMAN (229-428): 7.22e-42: 167: 21.89
+	Hs
		847050 SMCA4_HUMAN (18-526): 1.58e-30: 130: 13.06		FBXW7_HUMAN (229-428): 7.22e-42: 167: 21.89
+	Bt
		60990 A5PKJ3_BOVIN (221-655): 1.14e-24: 112: 17.45		LIS1_BOVIN (284-476): 2.16e-37: 148: 18.65
+	Hs
		1051392 DCTN1_HUMAN (88-572): 2.4e-12: 72.7: 10.41		FBXW7_HUMAN (229-428): 7.22e-42: 167: 21.89
+	Hs
		1268063 MY18A_HUMAN (329-637): 1.72e-11: 70: 17.67		FBXW7_HUMAN (229-428): 7.22e-42: 167: 21.89
+	Hs
		1281519 MRCKB_HUMAN (197-560): 2.09e-10: 66.2: 13.44		FBXW7_HUMAN (229-428): 7.22e-42: 167: 21.89
+	Hs
		1068625 PLEC_HUMAN (327-659): 1.61e-09: 63.5: 20.77		FBXW7_HUMAN (229-428): 7.22e-42: 167: 21.89
+	Hs
		792983 DCTN1_HUMAN (88-572): 2.4e-12: 72.7: 10.41		LIS1_HUMAN (284-476): 1.35e-37: 148: 18.65
+	Hs
		1145851 CP135_HUMAN (300-610): 1.6e-09: 63.5: 21.52		POC1B_HUMAN (275-524): 9.13e-38: 150: 16.40
+	Hs
		792997 CP135_HUMAN (300-610): 1.6e-09: 63.5: 21.52		LIS1_HUMAN (284-476): 1.35e-37: 148: 18.65
+	Hs
		197037 FKB15_HUMAN (49-548): 5.14e-10: 65: 9.00		PRP4_HUMAN (275-480): 1.56e-28: 123: 16.13
+	Hs
		1240468 MYO5C_HUMAN (318-668): 7.57e-17: 87.4: 12.02		POC1A_HUMAN (17-146): 1.4e-20: 97.7: 9.77
+	Hs
		148157 CTRO_HUMAN (327-578): 7.02e-09: 61.3: 16.36		PRP4_HUMAN (275-480): 1.56e-28: 123: 16.13
+	Hs
		728492 MYH11_HUMAN (141-564): 3.93e-11: 68.9: 11.53		POC1A_HUMAN (17-146): 1.4e-20: 97.7: 9.77
+	Hs
		1132663 FKB15_HUMAN (49-548): 5.14e-10: 65: 9.00		POC1A_HUMAN (17-146): 1.4e-20: 97.7: 9.77
+	Hs
		903399 MY18A_HUMAN (329-637): 1.72e-11: 70: 17.67		WDR5_HUMAN (367-521): 5.01e-11: 67.7: 10.97
+	Hs
		903240 PLEC_HUMAN (327-659): 1.61e-09: 63.5: 20.77		WDR5_HUMAN (367-521): 5.01e-11: 67.7: 10.97
+	Hs
		148610 CTRO_HUMAN (327-578): 7.02e-09: 61.3: 16.36		WDR5_HUMAN (367-521): 5.01e-11: 67.7: 10.97