HitPredict

Interactor 1: LZTS2 (Q9BRK4)
Leucine zipper putative tumor suppressor 2 (hLZTS2) (Protein LAPSER1)
Gene: LZTS2

Interactor 2: PKHG1 (Q9ULL1)
Pleckstrin homology domain-containing family G member 1
Gene: PLEKHG1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	29395067
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 669 Hs			1 1385
+	Hs
		1356647 MYH13_HUMAN (161-669): 3.57e-13: 75.4: 11.94		PKHG1_HUMAN (1-1385): 0: 1725: 100.00
+	Hs
		1145981 CP135_HUMAN (300-610): 1.6e-09: 63.5: 21.52		PKHG1_HUMAN (1-1385): 0: 1725: 100.00
+	Mm
		1141829 TSC1_MOUSE (48-630): 3.36e-32: 135: 13.67		ARHG2_MOUSE (3-763): 6.22e-111: 376: 13.45
+	Hs
		1051391 DCTN1_HUMAN (88-572): 2.4e-12: 72.7: 10.41		ARHG2_HUMAN (3-763): 1.1e-113: 383: 12.80
+	Hs
		1068630 PLEC_HUMAN (327-659): 1.61e-09: 63.5: 20.77		Q96D37_HUMAN (14-741): 1.1e-117: 389: 15.54
+	Hs
		548710 PLEC_HUMAN (327-659): 1.61e-09: 63.5: 20.77		VAV_HUMAN (14-741): 4.36e-117: 389: 15.54
+	Mm
		1118104 CC88B_MOUSE (153-516): 1.44e-09: 63.5: 15.39		ARHG2_MOUSE (3-763): 6.22e-111: 376: 13.45
+	Hs
		50607 MY18A_HUMAN (329-637): 1.72e-11: 70: 17.67		PKHG3_HUMAN (9-1193): 8.56e-102: 355: 30.27
+	Hs
		1078876 ITSN1_HUMAN (75-640): 4.07e-22: 104: 13.88		PREX1_HUMAN (67-500): 1.41e-85: 311: 21.05
+	Hs
		1169519 MYH4_HUMAN (261-669): 1.55e-12: 73.1: 12.32		FGD5_HUMAN (3-432): 1.42e-95: 340: 21.08
+	Hs
		1169490 MY18A_HUMAN (329-637): 1.72e-11: 70: 17.67		FGD5_HUMAN (3-432): 1.42e-95: 340: 21.08
+	Hs
		728488 MYH11_HUMAN (141-564): 3.93e-11: 68.9: 11.53		FGD5_HUMAN (3-432): 1.42e-95: 340: 21.08
+	Hs
		1169516 MRCKB_HUMAN (197-560): 2.09e-10: 66.2: 13.44		FGD5_HUMAN (3-432): 1.42e-95: 340: 21.08
+	Hs
		1068579 PLEC_HUMAN (327-659): 1.61e-09: 63.5: 20.77		FGD5_HUMAN (3-432): 1.42e-95: 340: 21.08
+	Mm
		57135 LZTS3_MOUSE (1-669): 3.91e-31: 131: 31.62		KALRN_MOUSE (63-688): 4.62e-71: 265: 20.12
+	Hs
		166486 FKB15_HUMAN (49-548): 5.14e-10: 65: 9.00		MCF2L_HUMAN (27-598): 1.62e-88: 315: 20.49
+	Hs
		1068677 PLEC_HUMAN (327-659): 1.61e-09: 63.5: 20.77		ARHG4_HUMAN (55-490): 5.39e-87: 301: 20.87
+	Rn
		222475 MRCKA_RAT (185-663): 4.24e-19: 94.3: 11.02		KALRN_RAT (63-688): 1.55e-71: 267: 20.36
+	Hs
		1068589 PLEC_HUMAN (327-659): 1.61e-09: 63.5: 20.77		ARHGP_HUMAN (84-516): 9.9e-84: 288: 22.37
+	Rn
		957077 MRCKB_RAT (277-560): 1.55e-10: 66.6: 14.98		KALRN_RAT (63-688): 1.55e-71: 267: 20.36