HitPredict

Interactor 1: LZTS2 (Q9BRK4)
Leucine zipper putative tumor suppressor 2 (hLZTS2) (Protein LAPSER1)
Gene: LZTS2

Interactor 2: CP131 (Q9UPN4)
Centrosomal protein of 131 kDa (5-azacytidine-induced protein 1) (Pre-acrosome localization protein 1)
Gene: CEP131

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.667

Property	Details
Experiments	28514442, 29395067, 33961781
Identification Methods	affinity chromatography technology, proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005813 - centrosome GO:0005829 - cytosol
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 669 Hs			1 1083
+	Hs
		724989 LZTS2_HUMAN (1-669): 6.28e-56: 203: 100.00		MYH9_HUMAN (117-841): 6.25e-23: 108: 9.26
+	Hs
		725035 MYO5C_HUMAN (318-668): 7.57e-17: 87.4: 12.02		MYH9_HUMAN (117-841): 6.25e-23: 108: 9.26
+	Hs
		502901 MYH3_HUMAN (321-655): 9.39e-13: 74: 14.93		MYH6_HUMAN (401-1083): 1.84e-23: 110: 10.69
+	Mm
		93570 DESP_MOUSE (337-641): 2.9e-11: 69.3: 18.65		MYH9_MOUSE (117-841): 8.48e-25: 114: 9.85
+	Rn
		361106 MYH6_RAT (324-644): 1.04e-11: 70.5: 15.01		MYH6_RAT (401-1083): 3.47e-23: 109: 10.69
+	Hs
		522657 MYH4_HUMAN (261-669): 1.55e-12: 73.1: 12.32		MYH7_HUMAN (454-1078): 2.77e-22: 106: 13.38
+	Hs
		724943 MY18A_HUMAN (329-637): 1.72e-11: 70: 17.67		MYH9_HUMAN (117-841): 6.25e-23: 108: 9.26
+	Hs
		502933 MYH3_HUMAN (321-655): 9.39e-13: 74: 14.93		MYH4_HUMAN (454-1054): 3.45e-20: 99.5: 11.86
+	Hs
		675167 DCTN1_HUMAN (88-572): 2.4e-12: 72.7: 10.41		CLIP1_HUMAN (56-826): 1.34e-18: 94.2: 8.40
+	Hs
		528432 MYH13_HUMAN (161-669): 3.57e-13: 75.4: 11.94		MYH8_HUMAN (119-702): 1.2e-16: 88: 7.30
+	Hs
		528435 MYH4_HUMAN (261-669): 1.55e-12: 73.1: 12.32		MYH8_HUMAN (119-702): 1.2e-16: 88: 7.30
+	Hs
		1068617 MY18A_HUMAN (329-637): 1.72e-11: 70: 17.67		PLEC_HUMAN (237-915): 7.61e-17: 88.6: 13.48
+	Rn
		222476 MRCKA_RAT (185-663): 4.24e-19: 94.3: 11.02		MRCKB_RAT (858-1082): 1.63e-09: 64.3: 13.60
+	Mm
		93578 DESP_MOUSE (337-641): 2.9e-11: 69.3: 18.65		PLEC_MOUSE (214-909): 7.69e-16: 85.5: 12.18
+	Dm
		404213 MYSA_DROME (329-654): 6.59e-14: 77.9: 14.65		MYSA_DROME (203-890): 3.08e-12: 73.5: 10.39
+	Ce
		361121 MYO1_CAEEL (325-646): 5.38e-14: 78.1: 19.17		MYO2_CAEEL (422-1081): 1.66e-11: 71.2: 14.09
+	Hs
		725097 MYH11_HUMAN (141-564): 3.93e-11: 68.9: 11.53		MYH10_HUMAN (115-657): 3.26e-14: 79.9: 9.29
+	Hs
		1051518 DCTN1_HUMAN (88-572): 2.4e-12: 72.7: 10.41		CP131_HUMAN (664-1083): 1.02e-11: 71.4: 11.40
+	Hs
		1268126 MY18A_HUMAN (329-637): 1.72e-11: 70: 17.67		MRCKB_HUMAN (228-728): 8.99e-12: 72: 11.27