HitPredict

Interactor 1: SRSF8 (Q9BRL6)
Serine/arginine-rich splicing factor 8 (Pre-mRNA-splicing factor SRP46) (Splicing factor SRp46) (Splicing factor, arginine/serine-rich 2B)
Gene: SRSF8

Interactor 2: LC7L2 (Q9Y383)
Putative RNA-binding protein Luc7-like 2
Gene: LUC7L2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.80	0.60	0.695

Property	Details
Experiments	26186194, 28514442, 33961781, 34133714
Identification Methods	affinity chromatography technology, two hybrid, anti tag coimmunoprecipitation
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0016607 - nuclear speck
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 282 Hs			1 392
+	Hs
		1310286 SRSF8_HUMAN (1-282): 5.34e-41: 144: 100.00		LUC7L_HUMAN (1-367): 3.39e-77: 244: 66.49
+	Hs
		1357566 PPIE_HUMAN (16-102): 3.36e-32: 122: 35.63		LC7L2_HUMAN (1-392): 1.49e-78: 249: 100.00
+	Hs
		1343078 PPIE_HUMAN (16-102): 3.36e-32: 122: 35.63		LUC7L_HUMAN (1-367): 3.39e-77: 244: 66.49
+	Hs
		1031502 PABP4_HUMAN (2-103): 9.14e-22: 96.7: 19.61		LC7L2_HUMAN (1-392): 1.49e-78: 249: 100.00
+	Hs
		1329991 PABP3_HUMAN (2-103): 2.88e-19: 89.4: 19.61		LC7L2_HUMAN (1-392): 1.49e-78: 249: 100.00
+	Sc
		376945 PABP_YEAST (2-103): 2.06e-20: 92.5: 19.61		LUC7_YEAST (5-248): 2.16e-65: 210: 30.95
+	Sc
		694273 PUB1_YEAST (12-99): 1.78e-17: 83.7: 20.46		LUC7_YEAST (5-248): 2.16e-65: 210: 30.95