HitPredict

Interactor 1: GPTC1 (Q9BRR8)
G patch domain-containing protein 1 (Evolutionarily conserved G-patch domain-containing protein)
Gene: GPATCH1

Interactor 2: WDR83 (Q9BRX9)
WD repeat domain-containing protein 83 (Mitogen-activated protein kinase organizer 1) (MAPK organizer 1)
Gene: WDR83

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.667

Property	Details
Experiments	26186194, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000398 - mRNA splicing, via spliceosome GO:0071013 - catalytic step 2 spliceosome
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 931 Hs			1 315
+	Hs
		209473 GPTC1_HUMAN (1-931): 0: 668: 100.00		PLRG1_HUMAN (2-312): 1.61e-88: 275: 23.15
+	Hs
		1288272 GPTC1_HUMAN (1-931): 0: 668: 100.00		SNR40_HUMAN (101-312): 1.44e-55: 185: 18.47
+	Hs
		1310460 GPTC1_HUMAN (1-931): 0: 668: 100.00		NLE1_HUMAN (184-315): 2.98e-35: 134: 22.54
+	Hs
		1310808 MDN1_HUMAN (135-914): 1.55e-112: 384: 12.59		WDR83_HUMAN (1-315): 2.96e-102: 303: 100.00
+	Ce
		1091084 GPTC1_CAEEL (8-813): 1.73e-104: 345: 24.91		Q19986_CAEEL (14-306): 1.84e-96: 288: 48.46
+	Sp
		1319487 YK96_SCHPO (9-683): 4.17e-98: 319: 19.28		YN55_SCHPO (28-288): 7.99e-72: 225: 41.60
+	Hs
		1345855 MDN1_HUMAN (135-914): 1.55e-112: 384: 12.59		NLE1_HUMAN (184-315): 2.98e-35: 134: 22.54
+	Sp
		293867 YK96_SCHPO (9-683): 4.17e-98: 319: 19.28		CWF17_SCHPO (28-294): 2.22e-21: 94.4: 27.05
+	Sp
		142001 YK96_SCHPO (9-683): 4.17e-98: 319: 19.28		PRP46_SCHPO (14-267): 6.43e-20: 91.7: 26.07
+	Sp
		195183 YK96_SCHPO (9-683): 4.17e-98: 319: 19.28		PRP17_SCHPO (224-306): 1.02e-11: 67.5: 16.47
+	Hs
		1264784 TITIN_HUMAN (290-908): 3.38e-10: 66.8: 11.22		SNR40_HUMAN (101-312): 1.44e-55: 185: 18.47