HitPredict

Interactor 1: RIOK1 (Q9BRS2)
Serine/threonine-protein kinase RIO1 (EC 2.7.11.1) (EC 3.6.3.-) (RIO kinase 1)
Gene: RIOK1

Interactor 2: DDX49 (Q9Y6V7)
Probable ATP-dependent RNA helicase DDX49 (EC 3.6.4.13) (DEAD box protein 49)
Gene: DDX49

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	21081503
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding GO:0005654 - nucleoplasm
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 568 Hs			1 483
+	Hs
		1271640 RIOK1_HUMAN (1-568): 0: 673: 100.00		DDX17_HUMAN (1-422): 1.62e-122: 375: 30.54
+	Hs
		134186 RIOK1_HUMAN (1-568): 0: 673: 100.00		DDX3X_HUMAN (1-411): 6.97e-123: 375: 29.79
+	Hs
		571575 RIOK1_HUMAN (1-568): 0: 673: 100.00		DDX5_HUMAN (1-415): 1.63e-121: 370: 30.07
+	Hs
		757740 RIOK1_HUMAN (1-568): 0: 673: 100.00		IF4A3_HUMAN (3-382): 2.76e-118: 354: 31.05
+	Hs
		1292642 RIOK1_HUMAN (1-568): 0: 673: 100.00		DDX27_HUMAN (4-452): 3.93e-71: 242: 33.91
+	Hs
		1254788 RIOK1_HUMAN (1-568): 0: 673: 100.00		DDX54_HUMAN (2-375): 3.51e-61: 216: 37.66
+	Sc
		753059 RIO1_YEAST (109-546): 5.16e-116: 354: 36.56		RRP3_YEAST (3-428): 2.11e-167: 483: 41.69
+	Sc
		624197 RIO1_YEAST (109-546): 5.16e-116: 354: 36.56		DBP2_YEAST (1-380): 2.4e-122: 369: 32.12
+	Sc
		624105 RIO2_YEAST (168-550): 2.83e-67: 226: 17.47		DBP2_YEAST (1-380): 2.4e-122: 369: 32.12
+	Sc
		770058 RIO2_YEAST (168-550): 2.83e-67: 226: 17.47		HAS1_YEAST (4-388): 8.41e-60: 206: 34.52