HitPredict

Interactor 1: SIKE1 (Q9BRV8)
Suppressor of IKBKE 1 (Suppressor of IKK-epsilon)
Gene: SIKE1

Interactor 2: TNIK (Q9UKE5)
TRAF2 and NCK-interacting protein kinase (EC 2.7.11.1)
Gene: TNIK

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	32640226, 32707033
Identification Methods	affinity chromatography technology, pull down
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 207 Hs			1 1360
+	Hs
		1346707 FGOP2_HUMAN (1-203): 1.23e-47: 158: 43.50		TNIK_HUMAN (1-1360): 0: 1235: 100.00
+	Hs
		1233551 FGOP2_HUMAN (1-203): 1.23e-47: 158: 43.50		MINK1_HUMAN (1-1360): 0: 1051: 60.43
+	Hs
		324869 SIKE1_HUMAN (1-207): 1.94e-70: 215: 100.00		M4K4_HUMAN (1-1360): 0: 970: 59.11
+	Hs
		91411 FGOP2_HUMAN (1-203): 1.23e-47: 158: 43.50		E7EN19_HUMAN (1-1360): 0: 979: 60.80
+	Hs
		324891 FGOP2_HUMAN (1-203): 1.23e-47: 158: 43.50		M4K4_HUMAN (1-1360): 0: 970: 59.11
+	Hs
		1310720 SIKE1_HUMAN (1-207): 1.94e-70: 215: 100.00		MRCKB_HUMAN (15-1330): 0: 661: 15.04
+	Hs
		1310712 SIKE1_HUMAN (1-207): 1.94e-70: 215: 100.00		STK26_HUMAN (16-400): 7.78e-113: 362: 38.27
+	Hs
		131600 SIKE1_HUMAN (1-207): 1.94e-70: 215: 100.00		STK25_HUMAN (20-410): 8.77e-113: 362: 37.91
+	Hs
		1310721 SIKE1_HUMAN (1-207): 1.94e-70: 215: 100.00		STK24_HUMAN (20-340): 2.15e-111: 359: 43.03
+	Hs
		1023126 FGOP2_HUMAN (1-203): 1.23e-47: 158: 43.50		STK4_HUMAN (5-482): 7.72e-121: 387: 33.06
+	Dm
		1249843 FGOP2_DROME (4-189): 6.51e-55: 178: 30.00		HIPPO_DROME (1-317): 1.07e-107: 357: 38.89
+	Hs
		1027445 FGOP2_HUMAN (1-203): 1.23e-47: 158: 43.50		STK3_HUMAN (4-485): 1.79e-115: 372: 29.28
+	Hs
		1240585 FGOP2_HUMAN (1-203): 1.23e-47: 158: 43.50		Q8NBY1_HUMAN (16-404): 1.5e-114: 366: 37.85
+	Hs
		131613 FGOP2_HUMAN (1-203): 1.23e-47: 158: 43.50		STK25_HUMAN (20-410): 8.77e-113: 362: 37.91
+	Hs
		1346705 FGOP2_HUMAN (1-203): 1.23e-47: 158: 43.50		STK26_HUMAN (16-400): 7.78e-113: 362: 38.27
+	Hs
		1346716 FGOP2_HUMAN (1-203): 1.23e-47: 158: 43.50		STK24_HUMAN (20-340): 2.15e-111: 359: 43.03