HitPredict

Interactor 1: WDR83 (Q9BRX9)
WD repeat domain-containing protein 83 (Mitogen-activated protein kinase organizer 1) (MAPK organizer 1)
Gene: WDR83

Interactor 2: DCA13 (Q9NV06)
DDB1- and CUL4-associated factor 13 (WD repeat and SOF domain-containing protein 1)
Gene: DCAF13

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.80	0.770

Property	Details
Experiments	26186194, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	eIF2A~WD40, Sof1~WD40, WD40~WD40
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 315 Hs			1 445
+	Dm
		1180742 Q9VYQ9_DROME (2-313): 9.5e-88: 272: 21.78		Q7KLW9_DROME (30-312): 6.42e-70: 231: 20.27
+	Hs
		1310825 WDR83_HUMAN (1-315): 2.96e-102: 303: 100.00		PRP19_HUMAN (169-372): 1.15e-22: 102: 13.53
+	Hs
		1288273 WDR83_HUMAN (1-315): 2.96e-102: 303: 100.00		SNR40_HUMAN (312-439): 6.18e-23: 101: 8.33
+	Hs
		792935 LIS1_HUMAN (63-312): 8.99e-76: 239: 19.78		LIS1_HUMAN (4-184): 1.13e-42: 157: 15.87
+	Mm
		925836 LIS1_MOUSE (63-312): 6.3e-76: 239: 19.78		LIS1_MOUSE (4-184): 9.82e-43: 157: 15.87
+	Hs
		209416 PLRG1_HUMAN (2-312): 1.61e-88: 275: 23.15		WDR5_HUMAN (311-444): 1.54e-27: 114: 9.49
+	Hs
		1240442 POC1B_HUMAN (2-181): 1.28e-52: 181: 21.43		POC1A_HUMAN (184-444): 1.19e-58: 199: 12.83
+	Hs
		209498 PLRG1_HUMAN (2-312): 1.61e-88: 275: 23.15		PRP19_HUMAN (169-372): 1.15e-22: 102: 13.53
+	Hs
		209467 PLRG1_HUMAN (2-312): 1.61e-88: 275: 23.15		SNR40_HUMAN (312-439): 6.18e-23: 101: 8.33
+	Hs
		236266 PRP17_HUMAN (8-304): 1.94e-87: 274: 23.40		PRP19_HUMAN (169-372): 1.15e-22: 102: 13.53
+	Hs
		236246 PRP17_HUMAN (8-304): 1.94e-87: 274: 23.40		SNR40_HUMAN (312-439): 6.18e-23: 101: 8.33
+	Hs
		863508 FBXW7_HUMAN (103-315): 7.36e-58: 199: 23.61		COPA_HUMAN (36-341): 1.01e-45: 171: 16.67
+	Dm
		1358845 WDS_DROME (2-266): 8.48e-80: 248: 22.99		WDS_DROME (311-444): 2.19e-27: 114: 9.49
+	Hs
		792949 LIS1_HUMAN (63-312): 8.99e-76: 239: 19.78		WDR5_HUMAN (311-444): 1.54e-27: 114: 9.49
+	Dm
		1358859 FBXW7_DROME (2-258): 1.53e-61: 213: 21.81		WDS_DROME (311-444): 2.19e-27: 114: 9.49
+	Hs
		903418 FBXW7_HUMAN (103-315): 7.36e-58: 199: 23.61		WDR5_HUMAN (311-444): 1.54e-27: 114: 9.49
+	Hs
		1281473 FBXW7_HUMAN (103-315): 7.36e-58: 199: 23.61		PRP19_HUMAN (169-372): 1.15e-22: 102: 13.53
+	Hs
		903428 SNR40_HUMAN (101-312): 1.44e-55: 185: 18.47		WDR5_HUMAN (311-444): 1.54e-27: 114: 9.49
+	Hs
		1288388 SNR40_HUMAN (101-312): 1.44e-55: 185: 18.47		PRP19_HUMAN (169-372): 1.15e-22: 102: 13.53
+	Hs
		1016312 SNR40_HUMAN (101-312): 1.44e-55: 185: 18.47		TBL3_HUMAN (289-436): 7.69e-11: 66.3: 5.13