HitPredict

Interactor 1: ERP44 (Q9BS26)
Endoplasmic reticulum resident protein 44 (ER protein 44) (ERp44) (Thioredoxin domain-containing protein 4)
Gene: ERP44

Interactor 2: EDEM3 (Q9BZQ6)
ER degradation-enhancing alpha-mannosidase-like protein 3 (EC 3.2.1.113) (Alpha-1,2-mannosidase EDEM3)
Gene: EDEM3

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	28366632
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005788 - endoplasmic reticulum lumen GO:0006986 - response to unfolded protein
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 406 Hs			1 932
+	Hs
		423351 PDIA1_HUMAN (40-350): 2.67e-17: 85.6: 11.11		EDEM3_HUMAN (1-932): 0: 1458: 100.00
+	Hs
		1220461 DJC10_HUMAN (19-353): 2.24e-13: 74: 13.07		EDEM3_HUMAN (1-932): 0: 1458: 100.00
+	Hs
		531974 PDIA4_HUMAN (18-350): 2.11e-12: 70.5: 9.43		EDEM3_HUMAN (1-932): 0: 1458: 100.00
+	Hs
		1240419 TXND5_HUMAN (31-144): 4.95e-12: 68.9: 33.33		EDEM3_HUMAN (1-932): 0: 1458: 100.00
+	Hs
		671915 PDIA3_HUMAN (18-349): 6.03e-11: 65.9: 9.63		EDEM3_HUMAN (1-932): 0: 1458: 100.00
+	Hs
		1268001 ERP44_HUMAN (1-406): 6.17e-123: 363: 100.00		EDEM1_HUMAN (43-514): 0: 605: 42.42
+	Hs
		423344 PDIA1_HUMAN (40-350): 2.67e-17: 85.6: 11.11		EDEM2_HUMAN (19-535): 0: 618: 37.62
+	Hs
		423311 PDIA1_HUMAN (40-350): 2.67e-17: 85.6: 11.11		EDEM1_HUMAN (43-514): 0: 605: 42.42
+	Hs
		1220441 DJC10_HUMAN (19-353): 2.24e-13: 74: 13.07		EDEM1_HUMAN (43-514): 0: 605: 42.42
+	Hs
		531924 PDIA4_HUMAN (18-350): 2.11e-12: 70.5: 9.43		EDEM1_HUMAN (43-514): 0: 605: 42.42
+	Sc
		690739 EUG1_YEAST (50-138): 1.65e-11: 67.8: 24.44		MNL1_YEAST (41-513): 0: 549: 35.28
+	Sc
		572779 PDI_YEAST (111-350): 7.6e-11: 65.5: 7.07		MNL1_YEAST (41-513): 0: 549: 35.28