HitPredict

Interactor 1: PSDE (O00487)
26S proteasome non-ATPase regulatory subunit 14 (EC 3.4.19.-) (26S proteasome regulatory subunit RPN11) (26S proteasome-associated PAD1 homolog 1)
Gene: PSMD14

Interactor 2: UCHL5 (Q9Y5K5)
Ubiquitin carboxyl-terminal hydrolase isozyme L5 (UCH-L5) (EC 3.4.19.12) (Ubiquitin C-terminal hydrolase UCH37) (Ubiquitin thioesterase L5)
Gene: UCHL5

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.95 0.60 0.756

The method score is based on:

Property Details
Experiments 26186194, 28514442, 33961781, 34761751, 19615732, 18922472, 24743594, 26496610, 35530310, 17323924, 19490896
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005829 - cytosol
GO:0006511 - ubiquitin-dependent protein catabolic process
GO:0031597 - cytosolic proteasome complex
and 2 others

more...
Homologous interactions 10

Homologous interactions

Color coding for hit scores

1 310
Hs

1 329
+ Hs
+ Sp
+ Hs
+ At
+ Hs
+ Hs
+ Mm
+ Hs
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024