HitPredict

Interactor 1: UBAC1 (Q9BSL1)
Ubiquitin-associated domain-containing protein 1 (UBA domain-containing protein 1) (Glialblastoma cell differentiation-related protein 1) (Kip1 ubiquitination-promoting complex protein 2)
Gene: UBAC1

Interactor 2: UBQL2 (Q9UHD9)
Ubiquilin-2 (Chap1) (DSK2 homolog) (Protein linking IAP with cytoskeleton 2) (PLIC-2) (hPLIC-2) (Ubiquitin-like product Chap1/Dsk2)
Gene: UBQLN2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.61	1.00	0.783

Property	Details
Experiments	32296183, unassigned1304
Identification Methods	two hybrid, two hybrid prey pooling approach, two hybrid array, validated two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	UBA~UBA, UBA~ubiquitin
Common GO terms	GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0031593 - polyubiquitin modification-dependent protein binding
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 405 Hs			1 624
+	Hs
		803722 UBAC1_HUMAN (1-405): 0: 579: 100.00		BAG6_HUMAN (21-580): 4.44e-53: 198: 15.23
+	Hs
		924140 UBAC1_HUMAN (1-405): 0: 579: 100.00		RS27A_HUMAN (33-119): 4.49e-24: 100: 27.27
+	Hs
		1273584 UBP13_HUMAN (168-335): 1.26e-43: 164: 24.59		UBQL2_HUMAN (1-624): 1.19e-153: 458: 100.00
+	Hs
		979370 UBXN1_HUMAN (191-276): 1.79e-20: 92.6: 37.50		UBQL2_HUMAN (1-624): 1.19e-153: 458: 100.00
+	Hs
		979375 UBXN1_HUMAN (191-276): 1.79e-20: 92.6: 37.50		UBQL1_HUMAN (1-624): 8.68e-147: 439: 71.52
+	Hs
		803679 UBP13_HUMAN (168-335): 1.26e-43: 164: 24.59		BAG6_HUMAN (21-580): 4.44e-53: 198: 15.23
+	Hs
		803499 UBXN1_HUMAN (191-276): 1.79e-20: 92.6: 37.50		BAG6_HUMAN (21-580): 4.44e-53: 198: 15.23
+	Hs
		800571 UBP5_HUMAN (168-326): 1.36e-40: 155: 21.62		RS27A_HUMAN (33-119): 4.49e-24: 100: 27.27
+	Dm
		547964 Q9VZU7_DROME (168-326): 7.2e-33: 133: 22.50		RS27A_DROME (33-103): 6.99e-13: 68.4: 33.33