HitPredict

Interactor 1: PCGF1 (Q9BSM1)
Polycomb group RING finger protein 1 (Nervous system Polycomb-1) (NSPc1) (RING finger protein 68)
Gene: PCGF1

Interactor 2: NANOG (Q9H9S0)
Homeobox protein NANOG (Homeobox transcription factor Nanog) (hNanog)
Gene: NANOG

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	26687479
Identification Methods	biochemical, affinity chromatography technology
Interaction Type	association, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0006355 - regulation of DNA-templated transcription
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 259 Hs			1 305
+	Hs
		718207 BMI1_HUMAN (30-255): 1.92e-63: 203: 35.29		NANOG_HUMAN (1-305): 3.02e-64: 206: 100.00
+	Hs
		718428 PCGF2_HUMAN (30-255): 4.65e-59: 192: 35.57		NANOG_HUMAN (1-305): 3.02e-64: 206: 100.00
+	Hs
		641545 PCGF1_HUMAN (1-259): 4.13e-82: 248: 100.00		PAX6_HUMAN (49-293): 3.5e-30: 119: 14.17
+	Hs
		679164 PCGF1_HUMAN (1-259): 4.13e-82: 248: 100.00		TLX1_HUMAN (26-221): 2.65e-30: 118: 23.47
+	Hs
		211952 PCGF1_HUMAN (1-259): 4.13e-82: 248: 100.00		TLX3_HUMAN (88-157): 1.29e-25: 104: 42.86
+	Hs
		1304113 RING2_HUMAN (24-259): 7.12e-39: 140: 16.88		NANOG_HUMAN (1-305): 3.02e-64: 206: 100.00
+	Hs
		585071 RO52_HUMAN (32-226): 9.58e-36: 134: 18.61		NANOG_HUMAN (1-305): 3.02e-64: 206: 100.00
+	Hs
		595583 BMI1_HUMAN (30-255): 1.92e-63: 203: 35.29		HXA5_HUMAN (2-165): 8.34e-36: 131: 20.69
+	Hs
		201868 BMI1_HUMAN (30-255): 1.92e-63: 203: 35.29		HXA3_HUMAN (41-216): 2e-33: 128: 24.86
+	Mm
		1194679 PCGF6_MOUSE (26-252): 3.04e-42: 149: 36.48		NANOG_MOUSE (1-303): 7.62e-40: 143: 54.98
+	Mm
		1194680 RING2_MOUSE (24-259): 5.08e-39: 140: 16.88		NANOG_MOUSE (1-303): 7.62e-40: 143: 54.98
+	Hs
		641552 PCGF6_HUMAN (26-252): 6.21e-45: 156: 36.05		PAX6_HUMAN (49-293): 3.5e-30: 119: 14.17
+	Hs
		641464 PCGF5_HUMAN (30-257): 3.38e-44: 151: 29.41		PAX6_HUMAN (49-293): 3.5e-30: 119: 14.17
+	Hs
		679129 PCGF5_HUMAN (30-257): 3.38e-44: 151: 29.41		TLX1_HUMAN (26-221): 2.65e-30: 118: 23.47
+	Hs
		213349 PCGF5_HUMAN (30-257): 3.38e-44: 151: 29.41		TLX2_HUMAN (76-157): 1.26e-27: 110: 37.35
+	Hs
		641538 RING2_HUMAN (24-259): 7.12e-39: 140: 16.88		PAX6_HUMAN (49-293): 3.5e-30: 119: 14.17
+	Hs
		679160 RING2_HUMAN (24-259): 7.12e-39: 140: 16.88		TLX1_HUMAN (26-221): 2.65e-30: 118: 23.47
+	Hs
		211899 PCGF5_HUMAN (30-257): 3.38e-44: 151: 29.41		TLX3_HUMAN (88-157): 1.29e-25: 104: 42.86
+	Hs
		641384 RING1_HUMAN (24-155): 3.14e-32: 123: 20.59		PAX6_HUMAN (49-293): 3.5e-30: 119: 14.17
+	Hs
		211843 RING1_HUMAN (24-155): 3.14e-32: 123: 20.59		TLX3_HUMAN (88-157): 1.29e-25: 104: 42.86