HitPredict

Interactor 1: BIN1 (O00499)
Myc box-dependent-interacting protein 1 (Amphiphysin II) (Amphiphysin-like protein) (Box-dependent myc-interacting protein 1) (Bridging integrator 1)
Gene: BIN1

Interactor 2: BIN1 (O00499)
Myc box-dependent-interacting protein 1 (Amphiphysin II) (Amphiphysin-like protein) (Box-dependent myc-interacting protein 1) (Bridging integrator 1)
Gene: BIN1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.69 1.00 0.835

The method score is based on:

Property Details
Experiments 10391921, unassigned1973, 23917616
Identification Methods pull down, two hybrid fragment pooling approach
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains BAR~BAR, SH3_9~SH3_9
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0002020 - protease binding
GO:0005543 - phospholipid binding
GO:0005634 - nucleus
GO:0005635 - nuclear envelope
and 49 others

more...
Homologous interactions 17

Homologous interactions

Color coding for hit scores

1 593
Hs

1 593
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+ Dm
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+ Sp
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+ Ca
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024