Interactor 1: CSN4 (Q9BT78)
COP9 signalosome complex subunit 4 (SGN4) (Signalosome subunit 4) (JAB1-containing signalosome subunit 4)
Gene: COPS4

Interactor 2: CSN7A (Q9UBW8)
COP9 signalosome complex subunit 7a (SGN7a) (Signalosome subunit 7a) (Dermal papilla-derived protein 10) (JAB1-containing signalosome subunit 7a)
Gene: COPS7A

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.89 1.00 0.947

The method score is based on:

Property Details
Experiments 19141280, 19295130, 23086934, 26496610, 27833851, 17403899
Identification Methods pull down, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains CSN4_RPN5_eIF3a~CSN7a_helixI, CSN4_RPN5_eIF3a~PCI, PCI~PCI
Common GO terms GO:0000338 - protein deneddylation
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
GO:0005829 - cytosol
and 3 others

more...

Homologous interactions 9

Homologous interactions

Color coding for hit scores

1 406
Hs

1 275
+ Hs
+ Dm
+ At
+ Hs
+ Hs
+ Ce
+ An
+ Dm
+ Sc

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024