Interactor 1: CSN4 (Q9BT78)
COP9 signalosome complex subunit 4 (SGN4) (Signalosome subunit 4) (JAB1-containing signalosome subunit 4)
Gene: COPS4

Interactor 2: CSN3 (Q9UNS2)
COP9 signalosome complex subunit 3 (SGN3) (Signalosome subunit 3) (JAB1-containing signalosome subunit 3)
Gene: COPS3

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.94 1.00 0.974

The method score is based on:

Property Details
Experiments 26186194, 28514442, 32034103, 33961781, 16036220, 20399188, 19295130, 24981860, 25043011, 9535219
Identification Methods affinity chromatography technology, pull down, chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains CSN4_RPN5_eIF3a~PCI, PCI~PCI
Common GO terms GO:0000338 - protein deneddylation
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
GO:0005829 - cytosol
and 3 others

more...

Homologous interactions 17

Homologous interactions

Color coding for hit scores

1 406
Hs

1 423
+ Mm
+ Hs
+ At
+ Dm
+ Hs
+ Dm
+ Hs
+ At
+ Ce
+ Ce
+ An
+ Hs
+ Dm
+ Sc
+ Dm
+ Sp
+ Sc

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024