Interactor 1: BIN1 (O00499)
Myc box-dependent-interacting protein 1 (Amphiphysin II) (Amphiphysin-like protein) (Box-dependent myc-interacting protein 1) (Bridging integrator 1)
Gene: BIN1

Interactor 2: TAU (P10636)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: MAPT

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.88 0.60 0.728

The method score is based on:

Property Details
Experiments 23399914, 25051234, 28755476, 26395440, 35063084
Identification Methods affinity chromatography technology, pull down, x-ray crystallography, nuclear magnetic resonance, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation, isothermal titration calorimetry
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0005886 - plasma membrane
GO:0030424 - axon
and 2 others

more...

Homologous interactions 13

Homologous interactions

Color coding for hit scores

1 593
Hs

1 758
+ Mm
+ Hs
+ Hs
+ Hs
+ Rn
+ Rn
+ Rn
+ Hs
+ Dm
+ Rn
+ Hs
+ Mm
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024