HitPredict

Interactor 1: CRDL1 (Q9BU40)
Chordin-like protein 1 (Neuralin-1) (Neurogenesin-1) (Ventroptin)
Gene: CHRDL1

Interactor 2: LRP1B (Q9NZR2)
Low-density lipoprotein receptor-related protein 1B (LRP-1B) (Low-density lipoprotein receptor-related protein-deleted in tumor) (LRP-DIT)
Gene: LRP1B

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 456 Hs			1 4599
+	Hs
		1048403 LAMA4_HUMAN (157-371): 8.87e-21: 97.7: 7.90		NID2_HUMAN (4360-4522): 5.4e-12: 74.9: 10.66
+	Hs
		433149 LAMB1_HUMAN (65-384): 4.95e-16: 83.1: 11.15		NID2_HUMAN (4360-4522): 5.4e-12: 74.9: 10.66
+	Hs
		624332 TENA_HUMAN (160-361): 1.82e-15: 81.5: 8.84		NID2_HUMAN (4360-4522): 5.4e-12: 74.9: 10.66
+	Dm
		422951 Q9W2H2_DROME (62-332): 1.45e-14: 78: 17.46		NOTCH_DROME (14-189): 1.52e-10: 70.3: 15.74
+	Hs
		1269006 SORL_HUMAN (13-331): 1.59e-10: 65.8: 10.89		SORL_HUMAN (4318-4575): 1.89e-12: 76.8: 11.24
+	Hs
		631066 LAMA1_HUMAN (1-239): 3.84e-10: 64.6: 12.55		NID2_HUMAN (4360-4522): 5.4e-12: 74.9: 10.66
+	Dm
		246971 TENM_DROME (217-372): 8.58e-13: 73.1: 11.63		Q9VBN0_DROME (4133-4367): 2.7e-09: 66: 15.36
+	Hs
		172664 LAMA5_HUMAN (13-238): 7.6e-10: 63.8: 11.74		NID2_HUMAN (4360-4522): 5.4e-12: 74.9: 10.66
+	Hs
		980481 PXDN_HUMAN (130-178): 2.12e-12: 71.5: 38.78		NOTC2_HUMAN (11-260): 3.49e-09: 66: 14.40
+	Dm
		422742 LAMA_DROME (14-238): 6.3e-11: 66.9: 10.22		NOTCH_DROME (14-189): 1.52e-10: 70.3: 15.74
+	Hs
		434638 TSP1_HUMAN (111-357): 5.38e-11: 66.9: 15.00		LRP2_HUMAN (4299-4586): 2.33e-10: 69.9: 9.18
+	Hs
		358511 CO1A1_HUMAN (37-113): 5.29e-09: 60.7: 28.21		NID2_HUMAN (4360-4522): 5.4e-12: 74.9: 10.66
+	Dm
		422715 LAMC1_DROME (64-299): 4.37e-09: 61.1: 12.15		NOTCH_DROME (14-189): 1.52e-10: 70.3: 15.74
+	Hs
		434641 TSP1_HUMAN (111-357): 5.38e-11: 66.9: 15.00		LRP1_HUMAN (5-268): 9.9e-09: 64.5: 14.24
+	Dm
		52257 LAMA_DROME (14-238): 6.3e-11: 66.9: 10.22		A1Z7C4_DROME (4354-4570): 8.46e-09: 64.5: 11.01
+	Hs
		980450 BMPER_HUMAN (140-326): 2.52e-10: 64.6: 20.00		NOTC2_HUMAN (11-260): 3.49e-09: 66: 14.40
+	Hs
		537530 LAMC3_HUMAN (64-290): 2.92e-09: 61.5: 12.07		NID1_HUMAN (3473-3718): 1.32e-09: 67.1: 13.83
+	Hs
		358465 CO1A1_HUMAN (37-113): 5.29e-09: 60.7: 28.21		NID1_HUMAN (3473-3718): 1.32e-09: 67.1: 13.83
+	Hs
		877404 LAMB2_HUMAN (15-280): 7.01e-09: 60.4: 9.62		NOTC2_HUMAN (11-260): 3.49e-09: 66: 14.40
+	Dm
		52252 LAMC1_DROME (64-299): 4.37e-09: 61.1: 12.15		A1Z7C4_DROME (4354-4570): 8.46e-09: 64.5: 11.01