HitPredict

Interactor 1: MED18 (Q9BUE0)
Mediator of RNA polymerase II transcription subunit 18 (Mediator complex subunit 18) (p28b)
Gene: MED18

Interactor 2: CDK19 (Q9BWU1)
Cyclin-dependent kinase 19 (EC 2.7.11.22) (CDC2-related protein kinase 6) (Cell division cycle 2-like protein kinase 6) (Cell division protein kinase 19) (Cyclin-dependent kinase 11) (Death-preventing kinase)
Gene: CDK19

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.80	0.60	0.694

Property	Details
Experiments	28514442, 33961781, 24981860, 23602568
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	3

Homologous interactions

Color coding for hit scores

	1 208 Hs			1 502
+	Hs
		826346 MED18_HUMAN (1-208): 1.09e-109: 314: 100.00		CDK8_HUMAN (1-502): 1.77e-150: 439: 76.69
+	Hs
		73040 MED18_HUMAN (1-208): 1.09e-109: 314: 100.00		B4DUB1_HUMAN (152-502): 1.59e-138: 406: 100.00
+	Dm
		1373829 MED18_DROME (19-207): 6.71e-77: 231: 54.12		CDK8_DROME (1-413): 7.19e-138: 407: 77.24