Interactor 1: MED18 (Q9BUE0)
Mediator of RNA polymerase II transcription subunit 18 (Mediator complex subunit 18) (p28b)
Gene: MED18

Interactor 2: MED20 (Q9H944)
Mediator of RNA polymerase II transcription subunit 20 (Mediator complex subunit 20) (TRF-proximal protein homolog) (hTRFP)
Gene: MED20

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.97 1.00 0.985

The method score is based on:

Property Details
Experiments 25416956, 25281560, 12584197, 32296183, 24981860, 35271311, 28514442, 33961781, 15989967, 20133760, 31515488, unassigned1304
Identification Methods two hybrid, proximity labelling technology, affinity chromatography technology, pull down, two hybrid prey pooling approach, two hybrid array, anti tag coimmunoprecipitation, mammalian protein protein interaction trap, validated two hybrid, tandem affinity purification
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Med18~Med20
Common GO terms GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0006357 - regulation of transcription by RNA polymerase II
GO:0016592 - mediator complex
GO:0032968 - positive regulation of transcription elongation by RNA polymerase II
and 3 others

more...

Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 208
Hs

1 212
+ Dm
+ At

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024