Interactor 1: MED18 (Q9BUE0)
Mediator of RNA polymerase II transcription subunit 18 (Mediator complex subunit 18) (p28b)
Gene: MED18

Interactor 2: MED4 (Q9NPJ6)
Mediator of RNA polymerase II transcription subunit 4 (Activator-recruited cofactor 36 kDa component) (ARC36) (Mediator complex subunit 4) (TRAP/SMCC/PC2 subunit p36 subunit) (Vitamin D3 receptor-interacting protein complex 36 kDa component) (DRIP36)
Gene: MED4

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.93 0.60 0.751

The method score is based on:

Property Details
Experiments 25281560, 24981860, 33961781, 35271311, 18250152, 28514442, 20133760
Identification Methods proximity labelling technology, affinity chromatography technology, anti tag coimmunoprecipitation, tandem affinity purification, pull down
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0003712 - transcription coregulator activity
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0006357 - regulation of transcription by RNA polymerase II
GO:0016592 - mediator complex
and 4 others

more...

Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 208
Hs

1 270
+ Dm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024