HitPredict

Interactor 1: MED18 (Q9BUE0)
Mediator of RNA polymerase II transcription subunit 18 (Mediator complex subunit 18) (p28b)
Gene: MED18

Interactor 2: MED29 (Q9NX70)
Mediator of RNA polymerase II transcription subunit 29 (Intersex-like protein) (Mediator complex subunit 29)
Gene: MED29

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.95	0.60	0.756

The method score is based on:

Property	Details
Experiments	15175163, 14638676, 14576168, 24981860, 33961781, 35271311, 28514442, 20133760, 24882805
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

The annotation score is based on:

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003712 - transcription coregulator activity GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0006357 - regulation of transcription by RNA polymerase II GO:0016592 - mediator complex and 4 others more... GO:0032968 - positive regulation of transcription elongation by RNA polymerase II GO:0051123 - RNA polymerase II preinitiation complex assembly GO:0060261 - positive regulation of transcription initiation by RNA polymerase II GO:0070847 - core mediator complex
Homologous interactions	1

Homologous interactions

Color coding for hit scores

	1	208
Hs

1	200

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024