Interactor 1: MED18 (Q9BUE0)
Mediator of RNA polymerase II transcription subunit 18 (Mediator complex subunit 18) (p28b)
Gene: MED18

Interactor 2: MED11 (Q9P086)
Mediator of RNA polymerase II transcription subunit 11 (Mediator complex subunit 11)
Gene: MED11

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.82 1.00 0.909

The method score is based on:

Property Details
Experiments 28514442, 33961781, 24981860, 35271311
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation, tandem affinity purification
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Med11~Med18
Common GO terms GO:0000151 - ubiquitin ligase complex
GO:0003712 - transcription coregulator activity
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0016592 - mediator complex
and 6 others

more...

Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 208
Hs

1 117
+ Dm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024