Interactor 1: MED18 (Q9BUE0)
Mediator of RNA polymerase II transcription subunit 18 (Mediator complex subunit 18) (p28b)
Gene: MED18

Interactor 2: MED13 (Q9UHV7)
Mediator of RNA polymerase II transcription subunit 13 (Activator-recruited cofactor 250 kDa component) (ARC250) (Mediator complex subunit 13) (Thyroid hormone receptor-associated protein 1) (Thyroid hormone receptor-associated protein complex 240 kDa component) (Trap240) (Vitamin D3 receptor-interacting protein complex component DRIP250) (DRIP250)
Gene: MED13

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.90 0.60 0.736

The method score is based on:

Property Details
Experiments 29568061, 24981860, 28514442, 33961781, 15989967, 20133760
Identification Methods proximity labelling technology, affinity chromatography technology, pull down, anti tag coimmunoprecipitation, tandem affinity purification
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0003712 - transcription coregulator activity
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0016592 - mediator complex
GO:0060261 - positive regulation of transcription initiation by RNA polymerase II
Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 208
Hs

1 2174
+ Hs
+ Dm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024