HitPredict

Interactor 1: BIN1 (O00499)
Myc box-dependent-interacting protein 1 (Amphiphysin II) (Amphiphysin-like protein) (Box-dependent myc-interacting protein 1) (Bridging integrator 1)
Gene: BIN1

Interactor 2: PIAS3 (Q9Y6X2)
E3 SUMO-protein ligase PIAS3 (EC 2.3.2.-) (E3 SUMO-protein transferase PIAS3) (Protein inhibitor of activated STAT protein 3)
Gene: PIAS3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.34	0.60	0.457

Property	Details
Experiments	unassigned1973
Identification Methods	two hybrid fragment pooling approach
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0005737 - cytoplasm
Homologous interactions	2

Homologous interactions

Color coding for hit scores

	1 593 Hs			1 628
+	Hs
		131183 BIN1_HUMAN (1-593): 1.03e-133: 404: 100.00		PIAS1_HUMAN (1-628): 0: 728: 56.69
+	Hs
		131184 BIN1_HUMAN (1-593): 1.03e-133: 404: 100.00		PIAS2_HUMAN (1-550): 0: 651: 59.00