Interactor 1: DERL1 (Q9BUN8)
Derlin-1 (Degradation in endoplasmic reticulum protein 1) (DERtrin-1) (Der1-like protein 1)
Gene: DERL1

Interactor 2: AMFR (Q9UKV5)
E3 ubiquitin-protein ligase AMFR (EC 2.3.2.36) (Autocrine motility factor receptor) (AMF receptor) (RING finger protein 45) (gp78)
Gene: AMFR

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.82 0.60 0.704

The method score is based on:

Property Details
Experiments 17872946, 32614325, 18216283, 16186510, 21832065
Identification Methods affinity chromatography technology, pull down
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005783 - endoplasmic reticulum
GO:0005789 - endoplasmic reticulum membrane
GO:0016020 - membrane
GO:0030968 - endoplasmic reticulum unfolded protein response
GO:0036503 - ERAD pathway
and 3 others

more...

Homologous interactions 8

Homologous interactions

Color coding for hit scores

1 251
Hs

1 643
+ Mm
+ Mm
+ Hs
+ Hs
+ Hs
+ Hs
+ Sc
+ Sc

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024