HitPredict

Interactor 1: DDX23 (Q9BUQ8)
Probable ATP-dependent RNA helicase DDX23 (EC 3.6.4.13) (100 kDa U5 snRNP-specific protein) (DEAD box protein 23) (PRP28 homolog) (U5-100kD)
Gene: DDX23

Interactor 2: TFP11 (Q9UBB9)
Tuftelin-interacting protein 11 (Septin and tuftelin-interacting protein 1) (STIP-1)
Gene: TFIP11

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.80 1.00 0.895

The method score is based on:

Property Details
Experiments 26186194, 28514442, 34079125, 33961781
Identification Methods affinity chromatography technology, proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains G-patch~Helicase_C
Common GO terms GO:0000398 - mRNA splicing, via spliceosome
GO:0005654 - nucleoplasm
GO:0005730 - nucleolus
GO:0071013 - catalytic step 2 spliceosome
Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 820
Hs

1 837
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024