HitPredict

Interactor 1: WDR18 (Q9BV38)
WD repeat-containing protein 18
Gene: WDR18

Interactor 2: SENP3 (Q9H4L4)
Sentrin-specific protease 3 (EC 3.4.22.-) (SUMO-1-specific protease 3) (Sentrin/SUMO-specific protease SENP3)
Gene: SENP3

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.85	0.60	0.718

Property	Details
Experiments	26186194, 28514442, 33961781, 22872859, 21326211
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation, pull down
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0005730 - nucleolus
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 432 Hs			1 574
+	Mm
		1118853 WDR18_MOUSE (1-432): 2.39e-85: 268: 83.10		SENP3_MOUSE (1-574): 0: 762: 94.60
+	Hs
		903515 WDR5_HUMAN (152-432): 8.2e-55: 186: 14.75		SENP3_HUMAN (1-574): 0: 683: 100.00
+	Hs
		903533 WDR5_HUMAN (152-432): 8.2e-55: 186: 14.75		SENP2_HUMAN (116-572): 7.43e-139: 417: 23.98
+	Hs
		1288354 SNR40_HUMAN (113-413): 1.61e-57: 194: 14.80		SENP1_HUMAN (257-572): 2.36e-112: 350: 29.08
+	Hs
		903566 WDR5_HUMAN (152-432): 8.2e-55: 186: 14.75		SENP1_HUMAN (257-572): 2.36e-112: 350: 29.08
+	Hs
		1346959 NLE1_HUMAN (1-106): 3.14e-28: 117: 19.63		SENP1_HUMAN (257-572): 2.36e-112: 350: 29.08
+	Hs
		1288295 SNR40_HUMAN (113-413): 1.61e-57: 194: 14.80		SENP6_HUMAN (466-564): 1.17e-19: 95.3: 27.45
+	Hs
		1326244 NLE1_HUMAN (1-106): 3.14e-28: 117: 19.63		SENP6_HUMAN (466-564): 1.17e-19: 95.3: 27.45