HitPredict

Interactor 1: WDR18 (Q9BV38)
WD repeat-containing protein 18
Gene: WDR18

Interactor 2: LAS1L (Q9Y4W2)
Ribosomal biogenesis protein LAS1L (Endoribonuclease LAS1L) (EC 3.1.-.-) (Protein LAS1 homolog)
Gene: LAS1L

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.83	0.60	0.709

Property	Details
Experiments	24981860, 33961781, 22872859, 37071682, 22190735
Identification Methods	affinity chromatography technology, cross-linking study, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0005730 - nucleolus GO:0006364 - rRNA processing
Homologous interactions	3

Homologous interactions

Color coding for hit scores

	1 432 Hs			1 734
+	Hs
		1288408 SNR40_HUMAN (113-413): 1.61e-57: 194: 14.80		LAS1L_HUMAN (1-734): 0: 1203: 100.00
+	Hs
		903643 WDR5_HUMAN (152-432): 8.2e-55: 186: 14.75		LAS1L_HUMAN (1-734): 0: 1203: 100.00
+	Sp
		194897 IPI3_SCHPO (5-337): 1.36e-76: 246: 24.46		LAS1_SCHPO (41-218): 1.56e-51: 188: 22.46