HitPredict

Interactor 1: VAMP8 (Q9BV40)
Vesicle-associated membrane protein 8 (VAMP-8) (Endobrevin) (EDB)
Gene: VAMP8

Interactor 2: STX18 (Q9P2W9)
Syntaxin-18 (Cell growth-inhibiting gene 9 protein)
Gene: STX18

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.667

Property	Details
Experiments	26186194, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005484 - SNAP receptor activity GO:0031201 - SNARE complex
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 100 Hs			1 335
+	Hs
		850602 VAMP7_HUMAN (1-100): 1.25e-26: 99.2: 38.00		STX18_HUMAN (1-335): 2.61e-130: 376: 100.00
+	Hs
		261736 VAMP4_HUMAN (7-80): 3.4e-25: 93.4: 29.73		STX18_HUMAN (1-335): 2.61e-130: 376: 100.00
+	Hs
		1079463 VAMP3_HUMAN (7-79): 2.36e-24: 89.9: 36.99		STX18_HUMAN (1-335): 2.61e-130: 376: 100.00
+	Dm
		1178117 Q7JYX5_DROME (1-100): 8.7e-32: 112: 32.00		Q9VC58_DROME (3-333): 4.05e-94: 286: 31.74