HitPredict

Interactor 1: RN126 (Q9BV68)
E3 ubiquitin-protein ligase RNF126 (EC 2.3.2.27) (RING finger protein 126)
Gene: RNF126

Interactor 2: UB2D4 (Q9Y2X8)
Ubiquitin-conjugating enzyme E2 D4 (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme D4) (HBUCE1) (Ubiquitin carrier protein D4) (Ubiquitin-protein ligase D4)
Gene: UBE2D4

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.74 1.00 0.862

The method score is based on:

Property Details
Experiments 32296183, 16189514, 19549727
Identification Methods two hybrid, two hybrid array, two hybrid pooling approach
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains UQ_con~zf-RING_2
Common GO terms GO:0005634 - nucleus
GO:0006511 - ubiquitin-dependent protein catabolic process
GO:0016567 - protein ubiquitination
GO:0035519 - protein K29-linked ubiquitination
GO:0044314 - protein K27-linked ubiquitination
and 2 others

more...
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 311
Hs

1 147
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024