HitPredict

Interactor 1: CP250 (Q9BV73)
Centrosome-associated protein CEP250 (250 kDa centrosomal protein) (Cep250) (Centrosomal Nek2-associated protein 1) (C-Nap1) (Centrosomal protein 2)
Gene: CEP250

Interactor 2: SYNCI (Q9H7C4)
Syncoilin (Syncoilin intermediate filament 1) (Syncoilin-1)
Gene: SYNC

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0048471 - perinuclear region of cytoplasm
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 2442 Hs			1 482
+	Hs
		443532 PLEC_HUMAN (3-1489): 1.72e-44: 181: 13.02		VIME_HUMAN (154-456): 2.16e-104: 321: 21.70
+	Hs
		1068542 PLEC_HUMAN (3-1489): 1.72e-44: 181: 13.02		AINX_HUMAN (170-456): 1.08e-91: 289: 25.25
+	Hs
		781898 PLEC_HUMAN (3-1489): 1.72e-44: 181: 13.02		PERI_HUMAN (154-456): 6.88e-79: 255: 22.50
+	Mm
		677677 PLEC_MOUSE (2-991): 1.82e-31: 138: 12.27		DESM_MOUSE (154-456): 2.87e-88: 279: 20.76
+	Hs
		821662 PLEC_HUMAN (3-1489): 1.72e-44: 181: 13.02		K2C6C_HUMAN (133-481): 3.14e-63: 216: 16.89
+	Hs
		148307 CTRO_HUMAN (633-1361): 7.89e-09: 63.5: 21.55		VIME_HUMAN (154-456): 2.16e-104: 321: 21.70
+	Hs
		148347 CTRO_HUMAN (633-1361): 7.89e-09: 63.5: 21.55		GFAP_HUMAN (154-456): 5.8e-99: 306: 23.27
+	Hs
		148869 CTRO_HUMAN (633-1361): 7.89e-09: 63.5: 21.55		AINX_HUMAN (170-456): 1.08e-91: 289: 25.25
+	Hs
		148372 CTRO_HUMAN (633-1361): 7.89e-09: 63.5: 21.55		DESM_HUMAN (154-456): 6.3e-86: 273: 20.76
+	Hs
		148487 CTRO_HUMAN (633-1361): 7.89e-09: 63.5: 21.55		PERI_HUMAN (154-456): 6.88e-79: 255: 22.50