HitPredict

Interactor 1: LST8 (Q9BVC4)
Target of rapamycin complex subunit LST8 (TORC subunit LST8) (G protein beta subunit-like) (Gable) (Protein GbetaL) (Mammalian lethal with SEC13 protein 8) (mLST8)
Gene: MLST8

Interactor 2: TF7L2 (Q9NQB0)
Transcription factor 7-like 2 (HMG box transcription factor 4) (T-cell-specific transcription factor 4) (T-cell factor 4) (TCF-4) (hTCF-4)
Gene: TCF7L2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 326 Hs			1 619
+	Hs
		903450 WDR5_HUMAN (79-326): 3.77e-74: 233: 20.57		CIC_HUMAN (43-578): 1.85e-33: 139: 15.01
+	Hs
		1343267 WDR3_HUMAN (9-256): 1.35e-19: 91.6: 14.00		TF7L2_HUMAN (1-619): 4e-84: 277: 100.00
+	Hs
		903155 WDR5_HUMAN (79-326): 3.77e-74: 233: 20.57		SRY_HUMAN (306-507): 4.03e-31: 122: 17.73
+	Hs
		903169 WDR5_HUMAN (79-326): 3.77e-74: 233: 20.57		SSRP1_HUMAN (333-511): 2.38e-26: 116: 18.89
+	Ce
		1089274 WDR51_CAEEL (1-250): 2.45e-66: 214: 17.58		SOX2_CAEEL (315-526): 8.43e-34: 132: 17.21
+	Hs
		817868 WDR5_HUMAN (79-326): 3.77e-74: 233: 20.57		SOX2_HUMAN (316-613): 5.49e-27: 113: 15.69
+	Hs
		331862 SNR40_HUMAN (199-318): 3.98e-24: 102: 20.00		NSD2_HUMAN (251-564): 1.22e-30: 130: 13.97
+	Hs
		197008 PRP4_HUMAN (157-324): 2.36e-27: 113: 18.75		SSRP1_HUMAN (333-511): 2.38e-26: 116: 18.89
+	Hs
		196970 PRP4_HUMAN (157-324): 2.36e-27: 113: 18.75		SOX2_HUMAN (316-613): 5.49e-27: 113: 15.69
+	Hs
		1074805 TAF5_HUMAN (162-323): 8.27e-18: 86.2: 19.14		CIC_HUMAN (43-578): 1.85e-33: 139: 15.01
+	Hs
		996824 SNR40_HUMAN (199-318): 3.98e-24: 102: 20.00		SSRP1_HUMAN (333-511): 2.38e-26: 116: 18.89
+	Hs
		1288324 SNR40_HUMAN (199-318): 3.98e-24: 102: 20.00		HM20A_HUMAN (250-461): 2.79e-27: 115: 14.15
+	Hs
		818610 WDR3_HUMAN (9-256): 1.35e-19: 91.6: 14.00		SOX2_HUMAN (316-613): 5.49e-27: 113: 15.69
+	Hs
		996881 TBL1R_HUMAN (198-321): 8.81e-19: 88.5: 23.08		SSRP1_HUMAN (333-511): 2.38e-26: 116: 18.89
+	Hs
		818441 TBL1R_HUMAN (198-321): 8.81e-19: 88.5: 23.08		SOX2_HUMAN (316-613): 5.49e-27: 113: 15.69
+	Mm
		1142008 TBL1R_MOUSE (198-321): 1.33e-18: 88.1: 23.08		Q60I23_MOUSE (318-613): 2.23e-26: 111: 14.47
+	Hs
		996930 NLE1_HUMAN (260-324): 3.72e-16: 80.8: 20.00		SSRP1_HUMAN (333-511): 2.38e-26: 116: 18.89
+	Hs
		989530 TAF5_HUMAN (162-323): 8.27e-18: 86.2: 19.14		SOX4_HUMAN (349-420): 8.6e-16: 82.5: 33.33