HitPredict

Interactor 1: TRI62 (Q9BVG3)
E3 ubiquitin-protein ligase TRIM62 (EC 2.3.2.27) (Tripartite motif-containing protein 62)
Gene: TRIM62

Interactor 2: UB2D4 (Q9Y2X8)
Ubiquitin-conjugating enzyme E2 D4 (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme D4) (HBUCE1) (Ubiquitin carrier protein D4) (Ubiquitin-protein ligase D4)
Gene: UBE2D4

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.61	0.60	0.606

Property	Details
Experiments	32296183, unassigned1304
Identification Methods	two hybrid, two hybrid prey pooling approach, two hybrid array, validated two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0004842 - ubiquitin-protein transferase activity GO:0016567 - protein ubiquitination GO:0044314 - protein K27-linked ubiquitination
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 475 Hs			1 147
+	Hs
		1336390 TRI39_HUMAN (2-472): 7.84e-148: 433: 29.94		UB2D4_HUMAN (1-147): 8.89e-84: 243: 100.00
+	Hs
		849453 TRI39_HUMAN (2-472): 7.84e-148: 433: 29.94		UB2D1_HUMAN (1-147): 4.61e-83: 241: 91.84
+	Hs
		919870 TRI39_HUMAN (2-472): 7.84e-148: 433: 29.94		UB2D2_HUMAN (1-147): 1.54e-82: 240: 93.20
+	Hs
		895921 TRI39_HUMAN (2-472): 7.84e-148: 433: 29.94		UB2D3_HUMAN (1-147): 1.56e-81: 238: 91.84
+	Hs
		584907 RO52_HUMAN (5-475): 2.05e-146: 428: 28.54		UB2D1_HUMAN (1-147): 4.61e-83: 241: 91.84
+	Hs
		584923 RO52_HUMAN (5-475): 2.05e-146: 428: 28.54		UB2D2_HUMAN (1-147): 1.54e-82: 240: 93.20
+	Hs
		584916 RO52_HUMAN (5-475): 2.05e-146: 428: 28.54		UB2D3_HUMAN (1-147): 1.56e-81: 238: 91.84
+	Hs
		1297370 TRI39_HUMAN (2-472): 7.84e-148: 433: 29.94		UB2E2_HUMAN (4-146): 3.5e-75: 224: 64.34
+	Hs
		1282350 TRI39_HUMAN (2-472): 7.84e-148: 433: 29.94		UB2E3_HUMAN (4-146): 1.24e-74: 223: 64.34
+	Hs
		536760 TRI27_HUMAN (1-473): 1.69e-138: 410: 28.05		UB2D1_HUMAN (1-147): 4.61e-83: 241: 91.84
+	Hs
		851889 TRI39_HUMAN (2-472): 7.84e-148: 433: 29.94		UB2E1_HUMAN (4-146): 4.67e-73: 218: 64.34
+	Hs
		536779 TRI27_HUMAN (1-473): 1.69e-138: 410: 28.05		UB2D2_HUMAN (1-147): 1.54e-82: 240: 93.20
+	Hs
		536772 TRI27_HUMAN (1-473): 1.69e-138: 410: 28.05		UB2D3_HUMAN (1-147): 1.56e-81: 238: 91.84
+	Hs
		584910 RO52_HUMAN (5-475): 2.05e-146: 428: 28.54		UB2E1_HUMAN (4-146): 4.67e-73: 218: 64.34
+	Hs
		896547 TRI39_HUMAN (2-472): 7.84e-148: 433: 29.94		UBE2N_HUMAN (4-147): 1.52e-69: 208: 46.53
+	Hs
		584918 RO52_HUMAN (5-475): 2.05e-146: 428: 28.54		UBE2N_HUMAN (4-147): 1.52e-69: 208: 46.53
+	Hs
		536965 TRI27_HUMAN (1-473): 1.69e-138: 410: 28.05		UB2E3_HUMAN (4-146): 1.24e-74: 223: 64.34
+	Hs
		536763 TRI27_HUMAN (1-473): 1.69e-138: 410: 28.05		UB2E1_HUMAN (4-146): 4.67e-73: 218: 64.34
+	Hs
		536757 TRI27_HUMAN (1-473): 1.69e-138: 410: 28.05		UBE2A_HUMAN (2-144): 4.45e-71: 211: 41.26
+	Hs
		536774 TRI27_HUMAN (1-473): 1.69e-138: 410: 28.05		UBE2N_HUMAN (4-147): 1.52e-69: 208: 46.53