HitPredict

Interactor 1: PTSS2 (Q9BVG9)
Phosphatidylserine synthase 2 (PSS-2) (PtdSer synthase 2) (EC 2.7.8.29) (Serine-exchange enzyme II)
Gene: PTDSS2

Interactor 2: P2Y12 (Q9H244)
P2Y purinoceptor 12 (P2Y12) (ADP-glucose receptor) (ADPG-R) (P2T(AC)) (P2Y(AC)) (P2Y(cyc)) (P2Y12 platelet ADP receptor) (P2Y(ADP)) (SP1999)
Gene: P2RY12

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	28514442
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0016020 - membrane
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 487 Hs			1 342
+	Hs
		849701 PTSS2_HUMAN (1-487): 0: 759: 100.00		CCR6_HUMAN (16-314): 3.66e-89: 273: 22.88
+	Hs
		782465 PTSS2_HUMAN (1-487): 0: 759: 100.00		P2RY2_HUMAN (17-304): 1.23e-71: 228: 24.22
+	Hs
		723394 PTSS2_HUMAN (1-487): 0: 759: 100.00		APJ_HUMAN (1-340): 9.92e-70: 224: 22.16
+	Hs
		781103 PTSS2_HUMAN (1-487): 0: 759: 100.00		OPRX_HUMAN (13-330): 8.68e-64: 208: 21.56
+	Hs
		876187 PTSS2_HUMAN (1-487): 0: 759: 100.00		PAR2_HUMAN (22-315): 3.79e-25: 106: 26.42
+	Hs
		814587 PTSS2_HUMAN (1-487): 0: 759: 100.00		P2RY1_HUMAN (28-309): 2.91e-19: 89.4: 24.40