HitPredict

Interactor 1: IMA4 (O00505)
Importin subunit alpha-4 (Importin alpha Q2) (Qip2) (Karyopherin subunit alpha-3) (SRP1-gamma)
Gene: KPNA3

Interactor 2: SMCA4 (P51532)
Transcription activator BRG1 (EC 3.6.4.-) (ATP-dependent helicase SMARCA4) (BRG1-associated factor 190A) (BAF190A) (Mitotic growth and transcription activator) (Protein BRG-1) (Protein brahma homolog 1) (SNF2-beta) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4)
Gene: SMARCA4

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 521 Hs			1 1647
+	Hs
		846901 IMA1_HUMAN (3-521): 1.35e-143: 425: 48.49		SMCA4_HUMAN (1-1647): 0: 1105: 100.00
+	Hs
		846902 IMA5_HUMAN (5-520): 3.45e-133: 398: 45.52		SMCA4_HUMAN (1-1647): 0: 1105: 100.00
+	Hs
		846725 IMA1_HUMAN (3-521): 1.35e-143: 425: 48.49		SMCA2_HUMAN (1-1647): 0: 980: 71.69
+	Hs
		846726 IMA5_HUMAN (5-520): 3.45e-133: 398: 45.52		SMCA2_HUMAN (1-1647): 0: 980: 71.69
+	Hs
		229344 IMA5_HUMAN (5-520): 3.45e-133: 398: 45.52		SMCA5_HUMAN (626-1631): 0: 835: 27.41
+	Hs
		658643 IMA5_HUMAN (5-520): 3.45e-133: 398: 45.52		SMCA1_HUMAN (639-1619): 0: 832: 28.82
+	Mm
		192636 IMA4_MOUSE (1-521): 2.11e-164: 478: 99.23		CHD8_MOUSE (18-1527): 0: 718: 20.36
+	Hs
		134899 IMA3_HUMAN (1-521): 1.68e-160: 468: 85.80		CHD4_HUMAN (482-1630): 0: 722: 23.79
+	Hs
		131423 IMA4_HUMAN (1-521): 9.9e-164: 476: 100.00		CHD3_HUMAN (300-1646): 0: 711: 20.80
+	Hs
		134969 IMA3_HUMAN (1-521): 1.68e-160: 468: 85.80		CHD8_HUMAN (13-1523): 0: 711: 21.11
+	Sc
		744898 IMA1_YEAST (8-521): 1.35e-134: 402: 45.22		ISW1_YEAST (550-1646): 0: 745: 25.77
+	Hs
		853286 IMA1_HUMAN (3-521): 1.35e-143: 425: 48.49		CHD4_HUMAN (482-1630): 0: 722: 23.79
+	Mm
		853539 IMA1_MOUSE (3-521): 1.6e-142: 422: 49.05		CHD8_MOUSE (18-1527): 0: 718: 20.36
+	Hs
		238679 IMA7_HUMAN (1-520): 9.33e-140: 415: 46.54		CHD4_HUMAN (482-1630): 0: 722: 23.79
+	Hs
		853257 IMA1_HUMAN (3-521): 1.35e-143: 425: 48.49		CHD3_HUMAN (300-1646): 0: 711: 20.80
+	Hs
		853480 IMA1_HUMAN (3-521): 1.35e-143: 425: 48.49		CHD8_HUMAN (13-1523): 0: 711: 21.11
+	Hs
		168636 IMA6_HUMAN (1-520): 1.1e-135: 405: 46.65		CHD4_HUMAN (482-1630): 0: 722: 23.79
+	Hs
		238743 IMA7_HUMAN (1-520): 9.33e-140: 415: 46.54		CHD8_HUMAN (13-1523): 0: 711: 21.11
+	Dm
		283986 O76522_DROME (6-521): 1.16e-140: 417: 67.89		CHDM_DROME (555-1640): 0: 704: 24.13
+	Hs
		168673 IMA6_HUMAN (1-520): 1.1e-135: 405: 46.65		CHD8_HUMAN (13-1523): 0: 711: 21.11