HitPredict

Interactor 1: IMA4 (O00505)
Importin subunit alpha-4 (Importin alpha Q2) (Qip2) (Karyopherin subunit alpha-3) (SRP1-gamma)
Gene: KPNA3

Interactor 2: HSF1 (Q00613)
Heat shock factor protein 1 (HSF 1) (Heat shock transcription factor 1) (HSTF 1)
Gene: HSF1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	27173435, 25036637
Identification Methods	affinity chromatography technology, tandem affinity purification, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol GO:0065003 - protein-containing complex assembly
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 521 Hs			1 529
+	Hs
		134878 IMA3_HUMAN (1-521): 1.68e-160: 468: 85.80		HSF1_HUMAN (1-529): 0: 610: 100.00
+	Hs
		853240 IMA1_HUMAN (3-521): 1.35e-143: 425: 48.49		HSF1_HUMAN (1-529): 0: 610: 100.00
+	Hs
		853568 IMA5_HUMAN (5-520): 3.45e-133: 398: 45.52		HSF1_HUMAN (1-529): 0: 610: 100.00
+	Dm
		283988 O76522_DROME (6-521): 1.16e-140: 417: 67.89		HSF_DROME (6-453): 1.06e-97: 312: 32.35