Interactor 1: SLX4 (Q8IY92)
Structure-specific endonuclease subunit SLX4 (BTB/POZ domain-containing protein 12)
Gene: SLX4
Interactor 2: MUS81 (Q96NY9)
Structure-specific endonuclease subunit MUS81 (EC 3.1.22.-) (Crossover junction endonuclease MUS81) (MUS81 endonuclease homolog)
Gene: MUS81
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.98 | 0.60 | 0.768 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 25416956, 21516116, 25224045, 28514442, 29850896, 32296183, 24012755, 25533185, 23033263, 23623386, 29892012, 31495888, 32398829, 37071664, 37059091, 19596235, 22902628, 21240275, 19595721, 19596236 and 4 others
more... |
| Identification Methods | two hybrid, affinity chromatography technology, pull down, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation, validated two hybrid, two hybrid array, two hybrid prey pooling approach |
| Interaction Type | direct interaction, physical association, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | - |
| Common GO terms | GO:0000712 - resolution of meiotic recombination intermediates GO:0003677 - DNA binding GO:0005654 - nucleoplasm GO:0006281 - DNA repair GO:0072429 - response to intra-S DNA damage checkpoint signaling |
| Homologous interactions | 2 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
